[HTML][HTML] Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer

X Li, Y Wang, S Deng, G Zhu, C Wang, NA Johnson… - Cancer cell, 2023 - cell.com
Tumor mutational burden and heterogeneity has been suggested to fuel resistance to many
targeted therapies. The cytosine deaminase APOBEC proteins have been implicated in the …

Signaling proteins in HSC fate determination are unequally segregated during asymmetric cell division

A Ugale, D Shunmugam, LG Pimpale, E Rebhan… - Journal of Cell …, 2024 - rupress.org
Signaling proteins in HSC fate determination are unequally segregated during asymmetric cell
division | Journal of Cell Biology | Rockefeller University Press Skip to Main Content …

[HTML][HTML] Asymmetric Cell Division of Hematopoietic Stem Cells: Recent Advances, Emerging Concepts, and Future Perspectives

J Nunes, D Loeffler - Frontiers in Hematology, 2024 - frontiersin.org
Hematopoietic stem cells (HSCs) can self-renew and differentiate for the entire life of an
organism to produce new blood cells when needed. This process is regulated by …