[HTML][HTML] Mitochondrial dysfunction: A fatal blow in depression

Y Song, H Cao, C Zuo, Z Gu, Y Huang, J Miao… - Biomedicine & …, 2023 - Elsevier
Mitochondria maintain the normal physiological function of nerve cells by producing
sufficient cellular energy and performing crucial roles in maintaining the metabolic balance …

Aerobic exercise, an effective prevention and treatment for mild cognitive impairment

B Huang, K Chen, Y Li - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
Aerobic exercise has emerged as a promising intervention for mild cognitive impairment
(MCI), a precursor to dementia. The therapeutic benefits of aerobic exercise are …

PI3K/AKT signaling activation by roflumilast ameliorates rotenone-induced Parkinson's disease in rats

HA Farid, RH Sayed, MES El-Shamarka… - …, 2024 - Springer
Parkinson's disease (PD) is the second most common progressive age-related
neurodegenerative disorder. Paramount evidence shed light on the role of PI3K/AKT …

Long-term lifestyle intervention is superior to transient modification for neuroprotection in D-galactose-induced aging rats

P Pantiya, C Thonusin, T Chunchai, H Pintana… - Life Sciences, 2023 - Elsevier
Aims To investigate whether transient dietary restriction or aerobic exercise in young
adulthood exert long-lasting protection against brain aging later in life. Main methods Seven …

[HTML][HTML] Adult hippocampal neurogenesis (AHN) controls central nervous system and promotes peripheral nervous system regeneration via physical exercise

V Zalouli, H Rajavand, M Bayat, J Khaleghnia… - Biomedicine & …, 2023 - Elsevier
Physical exercise has beneficial effects on adult hippocampal neurogenesis (AHN) and
cognitive processes, including learning. Although it is not known if anaerobic resistance …

Cognitive Fitness: Harnessing the Strength of Exerkines for Aging and Metabolic Challenges

M Saheli, M Moshrefi, M Baghalishahi, A Mohkami… - Sports, 2024 - mdpi.com
Addressing cognitive impairment (CI) represents a significant global challenge in health and
social care. Evidence suggests that aging and metabolic disorders increase the risk of CI …

Research Progress on Natural Plant Molecules in Regulating the Blood–Brain Barrier in Alzheimer's Disease

W Wu, J Huang, P Han, J Zhang, Y Wang, F Jin, Y Zhou - Molecules, 2023 - mdpi.com
Alzheimer's disease (AD) is a prevalent neurodegenerative disorder. With the aging
population and the continuous development of risk factors associated with AD, it will impose …

The principles of exercise prescription for brain health in aging

JJ Heisz, EE Waddington - Exercise, Sport, and Movement, 2023 - journals.lww.com
Alzheimer's disease and related dementias are among the world's greatest health
challenges. As the population ages, global dementia rates are rising, and with no imminent …

[HTML][HTML] Decrements in Both Physical and Cognitive Function Are Associated With a Higher Symptom Burden in Oncology Patients

D Sorrera, A Block, L Mackin, SM Paul… - Seminars in Oncology …, 2023 - Elsevier
Objectives Physical and cognitive function are two of the most important patient-reported
outcomes. In oncology patients receiving chemotherapy (N= 1331), purposes were to …

Exercise mimetics: a novel strategy to combat neuroinflammation and Alzheimer's disease

R Zhao - Journal of Neuroinflammation, 2024 - Springer
Neuroinflammation is a pathological hallmark of Alzheimer's disease (AD), characterized by
the stimulation of resident immune cells of the brain and the penetration of peripheral …