Cellular activation pathways and interaction networks in vascularized composite allotransplantation

L Knoedler, S Knoedler, AC Panayi, CAA Lee… - Frontiers in …, 2023 - frontiersin.org
Vascularized composite allotransplantation (VCA) is an evolving field of reconstructive
surgery that has revolutionized the treatment of patients with devastating injuries, including …

Acute rejection in vascularized composite allotransplantation

S Fischer, CG Lian, M Kueckelhaus… - Current opinion in …, 2014 - journals.lww.com
Acute rejection is higher in VCA than in any other organ in the field of transplantation,
although most episodes are controlled by high-dose steroids and optimization of …

First-in-human whole-eye transplantation: Ensuring an ethical approach to surgical innovation

M Laspro, E Thys, B Chaya, ED Rodriguez… - The American Journal …, 2024 - Taylor & Francis
As innovations in the field of vascular composite allotransplantation (VCA) progress, whole-
eye transplantation (WET) is poised to transition from non-human mammalian models to …

[HTML][HTML] Immune tolerance of human dental pulp-derived mesenchymal stem cells mediated by CD4+ CD25+ FoxP3+ regulatory T-cells and induced by TGF-β1 and IL …

JW Hong, JH Lim, CJ Chung, TJ Kang… - Yonsei Medical …, 2017 - ncbi.nlm.nih.gov
Purpose Most studies on immune tolerance of mesenchymal stem cells (MSCs) have been
performed using MSCs derived from bone marrow, cord blood, or adipose tissue. MSCs also …

Adipose-and bone marrow–derived mesenchymal stem cells prolong graft survival in vascularized composite allotransplantation

JA Plock, JT Schnider, W Zhang, R Schweizer… - …, 2015 - journals.lww.com
Background Strategies aiming at minimization or elimination of systemic
immunosuppression are key immediate goals for clinical expansion of vascularized …

The influence of timing and frequency of adipose-derived mesenchymal stem cell therapy on immunomodulation outcomes after vascularized composite …

JA Plock, JT Schnider, R Schweizer, W Zhang… - …, 2017 - journals.lww.com
Background Cellular therapies for immunomodulation in vascularized composite
allotransplantation (VCA) have gained importance due to their potential for minimization of …

Lessons learned from the first 15 years of penile transplantation and updates to the Baltimore Criteria

CD Lopez, AO Girard, IV Lake, BC Oh… - Nature Reviews …, 2023 - nature.com
Since 2006, five penis transplants have been performed worldwide. Mixed outcomes have
been reported, and two of the five penile transplants have required explantation. However …

Face transplantation—current status and future developments

S Tasigiorgos, B Kollar, N Krezdorn… - Transplant …, 2018 - Wiley Online Library
More than thirty‐five facial allograft transplantations (FAT) have been reported worldwide
since the pioneering case performed in France in the year 2005. FAT has received …

Local injections of tacrolimus-loaded hydrogel reduce systemic immunosuppression-related toxicity in vascularized composite allotransplantation

DV Dzhonova, R Olariu, J Leckenby, Y Banz… - …, 2018 - journals.lww.com
Background Routine application of vascularized composite allotransplantation is hampered
by immunosuppression-related health comorbidities. To mitigate these, we developed an …

Application possibilities of artificial intelligence in facial vascularized composite allotransplantation—a narrative review

L Knoedler, S Knoedler, O Allam, K Remy… - Frontiers in …, 2023 - frontiersin.org
Facial vascularized composite allotransplantation (FVCA) is an emerging field of
reconstructive surgery that represents a dogmatic shift in the surgical treatment of patients …