Sleep quality is often poor in patients with chronic obstructive pulmonary disease (COPD),
but these night-time symptoms are frequently unnoticed by physicians and/or not reported by …

Pulmonary delivery is an alternative route of administration with numerous advantages over
conventional routes of administration. It provides low enzymatic exposure, fewer systemic …

OBJECTIVES: COPD exacerbations are associated with significant morbidity and mortality.
This randomized, double-blind, parallel-group, multicenter study evaluated the effect of …

Abstract Background: This Phase III study evaluated the efficacy and safety of twice-daily
aclidinium 200 μg and 400 μg versus placebo in the treatment of moderate-to-severe COPD …

Prevention and treatment of COPD exacerbations are recognized as key goals in disease
management. This randomized, double-blind, parallel-group, multicenter study evaluated …

Background: Clinical trials measure exacerbations of chronic obstructive pulmonary disease
(COPD) inconsistently. A study was undertaken to determine if different methods for …

There is no single source of compiled data on symptoms experienced by patients with
chronic obstructive pulmonary disease (COPD) when awake and active throughout the day …

Chronic obstructive pulmonary disease (COPD) is a treatable disease characterized by
progressive airflow limitation. Prevention of disease progression, improvement of symptoms …

This retrospective analysis of data from two multi-center, randomized, double-blind, parallel
group studies compared the efficacy of fluticasone propionate/salmeterol (FSC) 250/50mcg …

The multicomponent nature of chronic obstructive pulmonary disease (COPD) has provided
a challenging environment in which to develop successful treatments. A combination of …