[HTML][HTML] Alcohol's effects on the brain: neuroimaging results in humans and animal models

NM Zahr, A Pfefferbaum - Alcohol research: current reviews, 2017 - ncbi.nlm.nih.gov
Brain imaging technology has allowed researchers to conduct rigorous studies of the
dynamic course of alcoholism through periods of drinking, sobriety, and relapse and to gain …

Neuropsychological assessment of hepatic encephalopathy: ISHEN practice guidelines

C Randolph, R Hilsabeck, A Kato… - Liver …, 2009 - Wiley Online Library
Low‐grade or minimal hepatic encephalopathy (MHE) is characterised by relatively mild
neurocognitive impairments, and occurs in a substantial percentage of patients with liver …

EASL Clinical Practice Guidelines on the management of hepatic encephalopathy

S Montagnese, PE Rautou, M Romero-Gómez… - Journal of …, 2022 - Elsevier
Summary The EASL Clinical Practice Guidelines (CPGs) on the management of hepatic
encephalopathy (HE) present evidence-based answers to a set of relevant questions (where …

Minimal hepatic encephalopathy: consensus statement of a working party of the Indian National Association for Study of the Liver

RK Dhiman, VA Saraswat, BK Sharma… - Journal of …, 2010 - Wiley Online Library
Hepatic encephalopathy (HE) is a major complication that develops in some form and at
some stage in a majority of patients with liver cirrhosis. Overt HE occurs in approximately 30 …

Hyperammonemia in hepatic encephalopathy

AR Jayakumar, MD Norenberg - Journal of clinical and experimental …, 2018 - Elsevier
The precise mechanism underlying the neurotoxicity of Hepatic Encephalopathy (HE) is
remains unclear. The dominant view has been that gut-derived nitrogenous toxins are not …

Cerebral effects of ammonia in liver disease: current hypotheses

P Ott, H Vilstrup - Metabolic brain disease, 2014 - Springer
Hyperammonemia is necessary for development of the cerebral complications to liver
disease including hepatic encephalopathy and cerebral edema but the mechanisms are …

Comparison of the most favoured methods for the diagnosis of hepatic encephalopathy in liver transplantation candidates

A Goldbecker, K Weissenborn, GH Shahrezaei… - Gut, 2013 - gut.bmj.com
Objective Hepatic encephalopathy (HE) is a common complication of liver insufficiency.
While there is widespread acceptance of its importance, there is no consensus on how best …

Systemic oxidative stress is implicated in the pathogenesis of brain edema in rats with chronic liver failure

CR Bosoi, X Yang, J Huynh, C Parent-Robitaille… - Free Radical Biology …, 2012 - Elsevier
Chronic liver failure leads to hyperammonemia, a central component in the pathogenesis of
hepatic encephalopathy (HE); however, a correlation between blood ammonia levels and …

Evidence for neuroinflammation and neuroprotection in HCV infection-associated encephalopathy

M Bokemeyer, XQ Ding, A Goldbecker, P Raab… - Gut, 2011 - gut.bmj.com
Objective Fatigue, mood disturbances and cognitive dysfunction are frequent in patients
infected with hepatitis C virus (HCV) who have mild liver disease. The reason is still unclear …

Validation of the psychometric hepatic encephalopathy score (PHES) for identifying patients with minimal hepatic encephalopathy

A Duarte-Rojo, J Estradas… - Digestive diseases and …, 2011 - Springer
Background The psychometric hepatic encephalopathy score (PHES) is a battery of
neuropsychological tests used in the diagnosis of minimal hepatic encephalopathy (MHE) …