Role of genetics and epigenetics in male infertility

S Gunes, SC Esteves - Andrologia, 2021 - Wiley Online Library
Male infertility is a complex condition with a strong genetic and epigenetic background. This
review discusses the importance of genetic and epigenetic factors in the pathophysiology of …

Clinical management of infertile men with nonobstructive azoospermia

SC Esteves - Asian journal of andrology, 2015 - journals.lww.com
The clinical management of men with nonobstructive azoospermia (NOA) seeking fertility
has been a challenge for andrologists, urologists, and reproductive medicine specialists …

Novel concepts in male factor infertility: clinical and laboratory perspectives

SC Esteves - Journal of assisted reproduction and genetics, 2016 - Springer
In recent years, the management of male factor infertility has undergone important changes
with the introduction of novel concepts, advanced testing, and therapeutic interventions. This …

The fate of leydig cells in men with spermatogenic failure

D Adamczewska, J Słowikowska-Hilczer… - Life, 2022 - mdpi.com
The steroidogenic cells in the testicle, Leydig cells, located in the interstitial compartment,
play a vital role in male reproductive tract development, maintenance of proper …

Post-Translational Modifications in sperm Proteome: The Chemistry of Proteome diversifications in the Pathophysiology of male factor infertility

L Samanta, N Swain, A Ayaz, V Venugopal… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Background The spermatozoa undergo a series of changes in the epididymis to mature after
their release from the testis and subsequently in the female reproductive tract after …

[HTML][HTML] Testicular sperm characteristics in men with nonobstructive azoospermia and their impact on intracytoplasmic sperm injection outcome

A Aboukhshaba, N Punjani, S Doukakis, N Zaninovic… - Fertility and …, 2022 - Elsevier
Objective To report fertilization and clinical pregnancy rates based on sperm characteristics
at the time of intracytoplasmic sperm injection (ICSI) in men with nonobstructive …

[HTML][HTML] The regenerative effect of bone marrow-derived stem cells in spermatogenesis of infertile hamster

A Vahdati, A Fathi, M Hajihoseini… - World journal of …, 2017 - ncbi.nlm.nih.gov
BACKGROUND Infertility is a serious social problem in advanced nations, with male factor in
half of all cases of infertility. This study was conducted to determine the regenerative effect of …

[HTML][HTML] Diagnosis and management of infertility due to ejaculatory duct obstruction: summary evidence

APP Achermann, SC Esteves - International braz j urol, 2021 - SciELO Brasil
Infertility, defined as the failure to conceive after one year of unprotected regular sexual
intercourse, affects approximately 15% of couples worldwide (1 1. Hamada A, Esteves SC …

[HTML][HTML] Azoospermia

M Sharma, S Leslie - StatPearls, 2023 - statpearls.com
Male factors are crucial contributors to infertility amongst infertile couples. The overall
incidence of infertility accounts for nearly 15% of the total population. Male infertility in its …

Exploring the dysregulated mRNAs–miRNAs–lncRNAs interactions associated to idiopathic non-obstructive azoospermia

S Sabetian, M Zarei, BN Jahromi… - Journal of …, 2022 - Taylor & Francis
Non-obstructive azoospermia (NOA) is the most clinical problem in case of infertility. About
70% of NOA patients are idiopathic with uncharacterized molecular mechanisms. This study …