Ancestry, Lipoprotein(a), and Cardiovascular Risk Thresholds: JACC Review Topic of the Week

S Tsimikas, SM Marcovina - Journal of the American College of Cardiology, 2022 - jacc.org
This study reviews ancestral differences in the genetics of the LPA gene, risk categories of
elevated lipoprotein (a)[Lp (a)] as defined by guidelines, ancestry-specific Lp (a) risk …

Apolipoprotein (a) isoforms and the risk of vascular disease: systematic review of 40 studies involving 58,000 participants

S Erqou, A Thompson, E Di Angelantonio… - Journal of the American …, 2010 - jacc.org
Objectives: The purpose of this study was to assess the association of apolipoprotein
(a)(apo [a]) isoforms with cardiovascular disease risk. Background: Although circulating …

Correlation between lipoprotein (a) and aortic valve sclerosis assessed by echocardiography (the JMS Cardiac Echo and Cohort Study)

T Gotoh, T Kuroda, M Yamasawa, M Nishinaga… - The American journal of …, 1995 - Elsevier
An elevated serum level of lipoprotein (a)(Lp [a]) may be an independent risk factor for
atherosclerotic disease, but the relation of Lp (a) to aortic valve (AV) sclerosis has not been …

Lipoprotein (a) as a risk factor for coronary artery disease

SM Marcovina, ML Koschinsky - The American journal of cardiology, 1998 - Elsevier
Since its identification by Kåre Berg in 1963, lipoprotein (a)[Lp (a)] has become a focus of
research interest owing to the results of case-control and prospective studies linking …

Efficacy and safety of pelacarsen in lowering Lp (a) in healthy Japanese subjects

E Karwatowska‑Prokopczuk, A Lesogor, JH Yan… - Journal of Clinical …, 2023 - Elsevier
Background Pelacarsen is a liver-targeted antisense oligonucleotide that potently lowers
lipoprotein (a)[Lp (a)] levels. Its safety and efficacy in diverse populations has not been …

Lipoprotein (a) in a randomly selected 25–64 year old population: the Northern Sweden Monica Study

L Slunga, K Asplund, O Johnson, GH Dahlén - Journal of clinical …, 1993 - Elsevier
Abstract Lipoprotein (a)(Lp (a)) was determined in 1527 individuals participating in the
Northern Sweden WHO MONICA project for monitoring of cardiovascular risk factors in the …

Lp (a): an acute-phase reactant?

A Noma, A Abe, S Maeda, M Seishima… - Chemistry and physics …, 1994 - Elsevier
The present study was designed to confirm the transient increases of plasma Lp (a) levels as
an acute-phase reactant and to clarify the significance of these increases with the use of …

[HTML][HTML] Influence of plasma lipoprotein (a) levels on coronary vasomotor response to acetylcholine

Y Tsurumi, H Nagashima, K Ichikawa… - Journal of the American …, 1995 - Elsevier
OBJECTIVES.: This study was undertaken to examine the influence of plasma lipoprotein
(a)[Lp (a)] levels on coronary endothelial vasomotor function. BACKGROUND …

Impact of lipoprotein (a) as residual risk on long-term outcomes in patients after percutaneous coronary intervention

H Konishi, K Miyauchi, T Kasai, S Tsuboi… - The American journal of …, 2015 - Elsevier
Cardiovascular risk remains uncertain in patients with cardiovascular disease despite
achieving target lipid levels. Serum levels of lipoprotein (a)[Lp (a)] can be risk factors for …

Lipoprotein (a): Cardiovascular risk and emerging therapies

M Fujino, SJ Nicholls - Expert Review of Cardiovascular Therapy, 2023 - Taylor & Francis
Introduction There is abundant evidence that elevated lipoprotein (a)[LP (a)] associates with
cardiovascular risk. Most lipid modifying therapies don't reduce Lp (a), but new technologies …