With all the advances in tissue engineering for construction of fully functional skin tissue,
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …

Inflammation is strictly associated with cancer and plays a key role in tumor development
and progression. Several epidemiological studies have demonstrated that inflammation can …

Importance An ongoing outbreak of COVID-19 has exhibited significant threats around the
world. We found a significant decrease of T lymphocyte subsets and an increase of …

Resident memory T cells (TRM) positioned within the respiratory tract are probably required
to limit SARS-CoV-2 spread and COVID-19. Importantly, TRM are mostly non-recirculating …

Natural killer (NK) cells, the large granular lymphocytes differentiated from the common
lymphoid progenitors, were discovered in early 1970's. They are members of innate …

The barrier surfaces of the gastrointestinal tract are in constant contact with various
microorganisms. Cytokines orchestrate the mucosal adaptive and innate immune cells in the …

Endometriosis is a chronic disease that affects about 10% of women of reproductive age. It
can contribute to pelvic pain, infertility or other conditions such as asthma, cardiovascular …

The immune system is a tightly regulated network which allows the development of defense
mechanisms against foreign antigens and tolerance toward self-antigens. Regulatory T cells …

Relapsed and refractory acute lymphoblastic leukemia (ALL) remains difficult to treat, with
minimal improvement in outcomes seen in more than 2 decades despite advances in upfront …

Interleukin-10 (IL-10) is a pleiotropic cytokine that has a fundamental role in modulating
inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory …