Involvement of the brain–heart axis in the link between PTSD and cardiovascular disease

AV Seligowski, TK Webber, PJ Marvar… - Depression and …, 2022 - Wiley Online Library
Posttraumatic stress disorder (PTSD) has long been associated with a heightened risk of
cardiovascular disease (CVD). A number of mechanisms have been implicated to underlie …

PTSD risk is associated with BDNF Val66Met and BDNF overexpression

L Zhang, DM Benedek, CS Fullerton, RD Forsten… - Molecular …, 2014 - nature.com
Brain-derived neurotrophic factor (BDNF), which regulates neuronal survival, growth,
differentiation and synapse formation, broadly regulates the stress response. 1 A common …

Individual differences in resting heart rate variability and cognitive control in posttraumatic stress disorder

BL Gillie, JF Thayer - Frontiers in psychology, 2014 - frontiersin.org
Post-traumatic stress disorder (PTSD) is characterized by deficits in cognitive functioning,
particularly cognitive control. Moreover, these deficits are thought to play a critical role in the …

Feasibility study of a wristband-type wearable sensor to understand construction workers' physical and mental status

H Jebelli, B Choi, H Kim, SH Lee - … Research Congress 2018, 2018 - ascelibrary.org
Poor work conditions and excessive physical demands associated with construction tasks
increase the risks associated with construction workers' impaired mental and physical …

Autonomic dysfunction and cardiovascular risk in post-traumatic stress disorder

Q Fu - Autonomic Neuroscience, 2022 - Elsevier
Background Patients with post-traumatic stress disorder (PTSD) have an increased risk for
cardiovascular disease. The underlying mechanisms are unclear but impaired autonomic …

Linking dimensional models of internalizing psychopathology to neurobiological systems: affect-modulated startle as an indicator of fear and distress disorders and …

U Vaidyanathan, CJ Patrick, BN Cuthbert - Psychological bulletin, 2009 - psycnet.apa.org
Integrative hierarchical models have sought to account for the extensive comorbidity
between various internalizing disorders in terms of broad individual difference factors these …

Severe, multimodal stress exposure induces PTSD-like characteristics in a mouse model of single prolonged stress

SA Perrine, AL Eagle, SA George, K Mulo… - Behavioural Brain …, 2016 - Elsevier
Appropriate animal models of posttraumatic stress disorder (PTSD) are needed because
human studies remain limited in their ability to probe the underlying neurobiology of PTSD …

Intranasal oxytocin reduces provoked symptoms in female patients with posttraumatic stress disorder despite exerting sympathomimetic and positive chronotropic …

M Sack, D Spieler, L Wizelman, G Epple, J Stich… - BMC medicine, 2017 - Springer
Background Posttraumatic stress disorder (PTSD) is a severe psychiatric disease
accompanied by neuroendocrine changes such as adrenergic overdrive and hence an …

[HTML][HTML] Impaired fear inhibition learning predicts the persistence of symptoms of posttraumatic stress disorder (PTSD)

M Sijbrandij, IM Engelhard, MJJ Lommen… - Journal of psychiatric …, 2013 - Elsevier
Recent cross-sectional studies have shown that the inability to suppress fear under safe
conditions is a key problem in people with posttraumatic stress disorder (PTSD). The current …

Critical evaluation of current data analysis strategies for psychophysiological measures of fear conditioning and extinction in humans

LJ Ney, M Wade, A Reynolds, DV Zuj, S Dymond… - International Journal of …, 2018 - Elsevier
Fear conditioning and extinction is a construct integral to understanding trauma-, stress-and
anxiety-related disorders. In the laboratory, associative learning paradigms that pair …