Abstract Serotonin (5-hydroxytrympamine or 5-HT) is one of the phylogenetically oldest
neurotransmitters, and the serotonergic system is among the earliest developed neuronal …

Excessive fear is a hallmark of several emotional and mental disorders such as phobias and
panic disorders. Considerable attention is focused on defining the neurobiological …

A concise review covering updated presence and role of 2-phenethylamines in medicinal
chemistry is presented. Open-chain, flexible alicyclic amine derivatives of this motif are …

Serotonin, or 5-hydroxytryptamine (5-HT), is a well-known neurotransmitter that plays vital
roles in neural activities and social behaviors. Clinically, deficiency of serotonin is linked …

Psychedelic compounds, including psilocybin, LSD, DMT, and 5-MeO-DMT all of which are
serotonin (5-HT) 2A receptor agonists are being investigated as potential treatments. This …

The serotonin 5-HT2A receptor is the major target of psychedelic drugs such as lysergic acid
diethylamide (LSD), mescaline, and psilocybin. Serotonergic psychedelics induce profound …

The association of chronic pain with depression is becoming increasingly recognized.
Treating both the conditions together is essential for an effective treatment outcome. In this …

Background Depression or Major depressive disorder (MDD) is a prolonged condition of
sadness. MDD is the most common mental disorder that affects more than 264 million …

Pharmacological and genetic tools targeting the 5-hydroxytryptamine (5-HT) 7 receptor in
preclinical animal models have implicated this receptor in diverse (patho) physiological …

To gain insight into the neurophysiological mechanisms involved in Zen meditation, we
evaluated the effects of focused attention (FA) on breathing movements in the lower …