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Progesterone receptor (PR) mediates the actions of the ovarian steroid progesterone, which
together with estradiol regulates gonadotropin secretion, prepares the endometrium for …

Background The efficacy and safety of oral ulipristal acetate for the treatment of symptomatic
uterine fibroids before surgery are uncertain. Methods We randomly assigned women with …

Uterine fibroids (also known as leiomyomas or myomas) are the most common form of
benign uterine tumors. Clinical presentations include abnormal bleeding, pelvic masses …

Background The efficacy and side-effect profile of ulipristal acetate as compared with those
of leuprolide acetate for the treatment of symptomatic uterine fibroids before surgery are …

Objective To investigate the efficacy and safety of ulipristal acetate (UPA) for long-term
treatment of symptomatic uterine fibroids. Design Repeated intermittent open-label UPA …

Objective To investigate the efficacy and safety of repeated 12-week courses of 5 or 10 mg
daily of ulipristal acetate for intermittent treatment of symptomatic uterine fibroids. Design …

BACKGROUND Uterine leiomyomas (fibroids) are highly prevalent benign smooth muscle
tumors of the uterus. In the USA, the lifetime risk for women developing uterine leiomyomas …

Uterine leiomyomas (fibroids or myomas) are benign tumors of uterus and clinically
apparent in a large part of reproductive aged women. Clinically, they present with a variety …

Nuclear receptors are ligand-activated transcription factors and include the receptors for
steroid hormones, lipophilic vitamins, sterols, and bile acids. These receptors serve as …