Current treatments for fibroids are mainly surgical and expensive, so alternatives need to be
found. It is, therefore, vital to develop and evaluate alternatives to surgical procedures …

Uterine fibroids may cause infertility, depending on their size and location according to the
International Federation of Gynecology and Obstetrics classification. In this review, infertility …

Uterine leiomyomas (ULs), frequent benign tumours of the female reproductive tract, are
associated with a range of symptoms and significant morbidity. Despite extensive research …

Background: The objective of this review is to determine the evidence or, conversely, the
absence of evidence regarding the effectiveness of progestogens in treating premenopausal …

Uterine fibroids are the most frequent benign tumours in women of child‐bearing age. Their
symptoms are diverse and the quality of life of the women affected can be significantly …

Introduction: We undertook a literature review of the use of levonorgestrel-releasing
intrauterine devices when utilized for heavy menstrual bleeding and/or dysmenorrhea …

Objective To identify and characterize myometrial/fibroid stem cells by specific stem cell
markers in human myometrium, and to better understand the stem cell contribution in the …

Background Progesterone, via its nuclear receptor (PR), exerts an overall tumorigenic effect
on both uterine fibroid (leiomyoma) and breast cancer tissues, whereas the antiprogestin …

Leiomyomas are smooth muscle tumors of the uterus and are the most common uterine
neoplasm. Although leiomyomas are usually asymptomatic, they can manifest with …

Objective To test whether mechanical substrate stiffness would influence progesterone
receptor B (PRB) signaling in fibroid cells. Uterine fibroids feature an excessive extracellular …