Current management of myomas: the place of medical therapy w... : Current Opinion in
Obstetrics and Gynecology Current management of myomas: the place of medical therapy with …

Selective progesterone receptor modulators (SPRMs) have been developed since the late
70s when mifepristone was first described. They act through nuclear progesterone receptors …

There has been a significant annual increase in the number of cases of uterine leiomyomas
or fibroids (UF) among women of all races and ages across the world. A fortune is usually …

Abstract Background Uterine Fibroids (UFs) growth is ovarian steroid-dependent. Previous
studies have shown that estrogen and progesterone play an important role in UF …

Introduction: Uterine fibroids (also known as leiomyomas or myomas) are the most common
form of benign uterine tumors. Current management strategies involve mainly surgical …

Миома матки была, есть и остается самым распространенным гинекологическим
заболеванием. По частоте постановки диагноза миома уступает лишь воспалительным …

Context Ulipristal acetate (UPA), a selective progesterone receptor modulator, clinically
reduces uterine myoma size in 80% of cases. However, the molecular mechanism of action …

Introduction: During the last decade, there has been increased emphasis on the role of
progesterone in the promotion of fibroid growth, as well as heightened interest in modulating …

Uterine myoma is the most common benign uterine tumor in women of reproductive age and
occurs in 20%–25% of the worldwide population. No currently approved medical treatment …

Uterine fibroids can significantly impact a woman's health, fertility, and quality of life. When
medical therapy fails, surgery is recommended; the gold standard in uterine-sparing surgery …