[HTML][HTML] Current understanding of somatic stem cells in leiomyoma formation

A Mas, I Cervello, C Gil-Sanchis, C Simón - Fertility and sterility, 2014 - Elsevier
Objective To provide a detailed summary of current scientific knowledge of somatic stem
cells (SSCs) in murine and human myometrium and their putative implication in leiomyoma …

Endocrine-disrupting chemicals and Vitamin D deficiency in the pathogenesis of uterine fibroids

H Elkafas, OA Badary, E Elmorsy, R Kamel… - Journal of advanced …, 2021 - journals.ekb.eg
Uterine fibroids (UFs) are the most prevalent gynecologic neoplasm, affecting 70–80% of
women over their lifespan. Although UFs are benign, they can become life-threatening and …

[HTML][HTML] Adlay (Coix lachryma-jobi L. var. ma-yuen Stapf.) Hull Extract and Active Compounds Inhibit Proliferation of Primary Human Leiomyoma Cells and Protect …

PH Lin, CK Shih, YT Yen, W Chiang, SM Hsia - Molecules, 2019 - mdpi.com
Uterine leiomyomas, also known as fibroids, are benign neoplasms of the uterus and have a
high incidence rate in women of reproductive age. Hysterectomy or myomectomy is the …

[HTML][HTML] The long-term trend of uterine fibroid burden in China from 1990 to 2019: A Joinpoint and Age–Period–Cohort study

X Liu, B Wang, Q Zhang, J Zhang, S Wang - Frontiers in Physiology, 2023 - frontiersin.org
Purpose: Uterine fibroids occur in 40%–60% of women and are symptomatic in 30% of the
patients by causing abnormal uterine bleeding, pelvic pressure, pain, and infertility. The …

Ulipristal acetate for the management of large uterine fibroids associated with heavy bleeding: a review

J Donnez, GE Courtoy, O Donnez… - Reproductive biomedicine …, 2018 - Elsevier
Ulipristal acetate (UPA), a selective progesterone receptor modulator (SPRM), offers new
therapeutic options for the clinical management of large uterine fibroids associated with …

[HTML][HTML] Ulipristal acetate decreases transforming growth factor β3 serum and tumor tissue concentrations in patients with uterine fibroids

M Ciebiera, M Włodarczyk, M Wrzosek… - Fertility and sterility, 2018 - Elsevier
Objective To evaluate and compare transforming growth factor β3 (TGF-β3) serum
concentration in patients with uterine fibroids (UFs) without hormone treatment, treated with …

Gene expression changes in uterine myomas in response to ulipristal acetate treatment

GE Courtoy, J Donnez, J Ambroise, P Arriagada… - Reproductive …, 2018 - Elsevier
Research question Does ulipristal acetate (UPA) modify the expression of genes related to
apoptosis or the extracellular matrix in uterine myomas and are any modifications …

[HTML][HTML] Uterine fibroids and longitudinal profiles of the vaginal microbiota in a cohort presenting for transvaginal ultrasound

SJ Robbins, SE Brown, CA Stennett, S Tuddenham… - Plos one, 2024 - journals.plos.org
Bacterial vaginosis, characterized in part by low levels of vaginal Lactobacillus species, has
been associated with pro-inflammatory cytokines which could fuel uterine fibroid …

Expression profiling of nuclear receptors identifies key roles of NR4A subfamily in uterine fibroids

H Yin, JH Lo, JY Kim, EE Marsh, JJ Kim… - Molecular …, 2013 - academic.oup.com
Uterine fibroids (UFs), also known as uterine leiomyomas, are benign, fibrotic smooth
muscle tumors. Although the GnRH analog leuprolide acetate that suppresses gonadal …

An integrated serum and urinary metabonomic research of Rhizoma Curcumae-Rhizoma Sparganii drug pair in hysteromyoma rats based on UPLC-Q-TOF-MS …

W Li, B Hong, Q Li, Z Li, K Bi - Journal of Ethnopharmacology, 2019 - Elsevier
Abstract Ethnopharmacological relevance Rhizoma Curcumae and Rhizoma Sparganii
(RCRS), a celebrated traditional Chinese medicine drug pair, has been used to treat …