A-kinase anchoring protein 13 (AKAP13) augments progesterone signaling in uterine fibroid cells

SSM Ng, S Jorge, M Malik, J Britten… - The Journal of …, 2019 - academic.oup.com
Context Uterine leiomyomata (fibroids) are prevalent sex hormone‒dependent tumors with
an altered response to mechanical stress. Ulipristal acetate, a selective progesterone …

Uterine fibroids: bridging genomic defects and chronic inflammation

A El Andaloussi, Z Chaudhry… - Seminars in …, 2017 - thieme-connect.com
Uterine fibroids (UF; aka leiomyoma, myomas) are the most common benign tumors of
female reproductive tract. They are highly prevalent, with 70 to 80% of women burdened by …

Influence of Ulipristal Acetate Therapy on Uterine Fibroid‐Related Symptoms and on Uterine and Fibroid Volumes and Vascularity Indices Assessed by Ultrasound

S Baggio, P Pomini, F Galeone, F Presti… - … of Ultrasound in …, 2018 - Wiley Online Library
Objectives To investigate the modifications of uterine and fibroid volume, to study Doppler
changes in uterine arteries and fibroid‐supplying vessels, and to assess possible …

[HTML][HTML] In Vivo Effects of Bay 11-7082 on Fibroid Growth and Gene Expression: A Preclinical Study

TD Chuang, N Ton, S Rysling, O Khorram - Cells, 2024 - mdpi.com
Current medical therapies for fibroids have major limitations due to their hypoestrogenic side
effects. Based on our previous work showing the activation of NF-kB in fibroids, we …

[HTML][HTML] Миома матки. Современные вопросы патогенеза и медикаментозной редукционной терапии

ЮЭ Доброхотова, АС Хачатрян, ДМ Ибрагимова - Доктор. ру, 2013 - cyberleninka.ru
Цель работы: анализ современных вопросов патогенеза миомы матки и ее
медикаментозной редукционной терапии. Основные положения. Несомненная роль …

The Rising Phoenix‐Progesterone as the Main Target of the Medical Therapy for Leiomyoma

HH Chill, M Safrai, A Reuveni Salzman… - BioMed research …, 2017 - Wiley Online Library
Leiomyomas, also known as uterine fibroids, are a common benign tumor in women of
reproductive age. These lesions disrupt the function of the uterus causing menorrhagia and …

Temperature-dependent dielectric properties of human uterine fibroids over microwave frequencies

G Zia, J Sebek, P Prakash - Biomedical Physics & Engineering …, 2021 - iopscience.iop.org
Microwave ablation is under investigation as a minimally-invasive treatment for uterine
fibroids. Computational models play a vital role in the development, evaluation and …

Effect of Isopropanolic Cimicifuga racemosa Extract on Uterine Fibroids in Comparison with Tibolone among Patients of a Recent Randomized, Double Blind, Parallel …

S Xi, E Liske, S Wang, J Liu, Z Zhang… - Evidence‐Based …, 2014 - Wiley Online Library
Objective. Effect of isopropanolic Cimicifuga racemosa extract (iCR) on uterine fibroid size
compared with tibolone. Method. The randomized, double‐blind, controlled study in China …

Миома матки и аденомиоз: молекулярная характеристика по экспрессии генов стероидных рецепторов

СВ Шрамко, ЛФ Гуляева, ЛГ Баженова… - Акушерство и …, 2018 - elibrary.ru
Цель исследования. Изучить особенности реагирования эндометрия и миометрия на
стероидную стимуляцию путем определения уровня экспрессии генов стероидных …

Prolactin is expressed in uterine leiomyomas and promotes signaling and fibrosis in myometrial cells

A DiMauro, C Seger, B Minor, AM Amitrano… - Reproductive …, 2022 - Springer
Uterine leiomyomas are benign, estrogen-sensitive, fibrotic smooth muscle cell tumors
occurring in the uterine myometrium. Leiomyomas are a considerable health burden, with a …