During the last few decades, the micronutrient zinc has proven to be an important metal ion
for a well-functioning immune system, and thus also for a suitable immune defense …

From bacteria to plants and humans, the glutathione system plays a pleiotropic role in cell
defense against metabolic, oxidative and metal stresses. Glutathione (GSH), the γ-L …

Normothermic machine perfusion (NMP) has emerged as an innovative organ preservation
technique. Developing an understanding for the donor organ immune cell composition and …

Macrophages are involved in immune defense, organogenesis and tissue homeostasis.
Macrophages contribute to the different phases of mammary gland remodeling during …

The purpose of this study was to determine the toxicological and pharmacokinetic properties
of sucralose-6-acetate, a structural analog of the artificial sweetener sucralose. Sucralose-6 …

Hepatocellular carcinoma (HCC) is the most familiar primary hepatic malignancy with a poor
prognosis. The incidence of HCC and the associated deaths have risen in recent decades …

Objective Systemic sclerosis (SSc) is a multifactorial autoimmune fibrotic disorder involving
complex rewiring of cell‐intrinsic and cell‐extrinsic signaling coexpression networks …

Parkinson's disease (PD) is characterized by motor symptoms based on a loss of
nigrostriatal dopaminergic neurons and by non-motor symptoms which precede motor …

Background/Aims Hepatocellular carcinoma (HCC), accounting for 75-85% of primary liver
cancer cases, is the third leading cause of cancer-related death worldwide. The purpose of …

Background Though immune checkpoint inhibitors (ICIs) exhibit durable efficacy in bladder
carcinomas (BLCAs), there are still a large portion of patients insensitive to ICIs treatment …