Surf4 (Surfeit Locus Protein 4) deficiency reduces intestinal lipid absorption and secretion and decreases metabolism in mice
G Tao, H Wang, Y Shen, L Zhai, B Liu… - … and Vascular Biology, 2023 - Am Heart Assoc
Background: Postprandial dyslipidemia is a causative risk factor for cardiovascular disease.
The majority of absorbed dietary lipids are packaged into chylomicron and then delivered to …
The majority of absorbed dietary lipids are packaged into chylomicron and then delivered to …
[HTML][HTML] Investigating the role of zinc in atherosclerosis: a review
T Shen, Q Zhao, Y Luo, T Wang - Biomolecules, 2022 - mdpi.com
Zinc, an indispensable micronutrient for human health, might play an important role in the
development of atherosclerosis. Zinc could be involved in the atherogenic process through …
development of atherosclerosis. Zinc could be involved in the atherogenic process through …
[HTML][HTML] Cuproptosis depicts tumor microenvironment phenotypes and predicts precision immunotherapy and prognosis in bladder carcinoma
H Li, X Zu, J Hu, Z Xiao, Z Cai, N Gao… - Frontiers in …, 2022 - frontiersin.org
Background Though immune checkpoint inhibitors (ICIs) exhibit durable efficacy in bladder
carcinomas (BLCAs), there are still a large portion of patients insensitive to ICIs treatment …
carcinomas (BLCAs), there are still a large portion of patients insensitive to ICIs treatment …
Metallothionein-2: An emerging target in inflammatory diseases and cancers
XL Wang, M Schnoor, LM Yin - Pharmacology & therapeutics, 2023 - Elsevier
Abstract Metallothionein-2 (MT-2) was originally discovered as a mediator of zinc
homeostasis and cadmium detoxification. However, MT-2 has recently received increased …
homeostasis and cadmium detoxification. However, MT-2 has recently received increased …
[HTML][HTML] Catalytic activity-modulated etching of plasmonic gold nanorods enabled ultra-sensitive colorimetric strategy for Early-Stage cancer diagnosis
While the aberrant low expression of metallothioneins (MTs) in tissue has been recognized
as an effective indicator to spot the occurrence of early-stage malignant tumors, the ultra …
as an effective indicator to spot the occurrence of early-stage malignant tumors, the ultra …
Cell Type–Specific Biomarkers of Systemic Sclerosis Disease Severity Capture Cell‐Intrinsic and Cell‐Extrinsic Circuits
JS Berkowitz, T Tabib, H Xiao, GM Sadej… - Arthritis & …, 2023 - Wiley Online Library
Objective Systemic sclerosis (SSc) is a multifactorial autoimmune fibrotic disorder involving
complex rewiring of cell‐intrinsic and cell‐extrinsic signaling coexpression networks …
complex rewiring of cell‐intrinsic and cell‐extrinsic signaling coexpression networks …
Distinct brain proteomic signatures in cerebral small vessel disease rat models of hypertension and cerebral amyloid angiopathy
JM Schrader, A Stanisavljevic, F Xu… - … of Neuropathology & …, 2022 - academic.oup.com
Cerebral small vessel diseases (CSVDs) are prominent contributors to vascular cognitive
impairment and dementia and can arise from a range of etiologies. Cerebral amyloid …
impairment and dementia and can arise from a range of etiologies. Cerebral amyloid …
[HTML][HTML] Single cell analysis of docosahexaenoic acid suppression of sequential LPS-induced proinflammatory and interferon-regulated gene expression in the …
KA Wierenga, FM Riemers, B Westendorp… - Frontiers in …, 2022 - frontiersin.org
Preclinical and clinical studies suggest that consumption of long chain omega-3
polyunsaturated fatty acids (PUFAs) reduces severity of chronic inflammatory and …
polyunsaturated fatty acids (PUFAs) reduces severity of chronic inflammatory and …
[HTML][HTML] Cannabidiol modulates expression of type I IFN response genes and HIV infection in macrophages
Cannabis (Cannabis sativa) is a widely used drug in the United States and the frequency of
cannabis use is particularly high among people living with HIV (PLWH). One key component …
cannabis use is particularly high among people living with HIV (PLWH). One key component …
[HTML][HTML] Oncostatin M signaling drives cancer-associated skeletal muscle wasting
Progressive weakness and muscle loss are associated with multiple chronic conditions,
including muscular dystrophy and cancer. Cancer-associated cachexia, characterized by …
including muscular dystrophy and cancer. Cancer-associated cachexia, characterized by …