Based on the diverse physiological influence, the impact of glial cells has become much
more evident on neurological illnesses, resulting in the origins of many diseases appearing …

Lifestyle factors such as intellectual stimulation, cognitive and social engagement, nutrition,
and various types of exercise appear to reduce the risk for common age-associated …

Background Brain innate immunity is vital for maintaining normal brain functions. Immune
homeostatic imbalances play pivotal roles in the pathogenesis of neurological diseases …

The NG2 proteoglycan is a type 1-transmembrane protein expressed by a range of cell types
within and outside the mammalian nervous system. NG2-expressing (NG2) cells are found …

Oligodendrocytes (OLs) are particularly susceptible to the toxicity of the acute lesion
environment after spinal cord injury (SCI). They undergo both necrosis and apoptosis …

Spinal cord injury results in cell loss, disruption of neural circuitry and chronic functional
impairment. Several different cell types generate progeny in response to injury, which …

Oligodendrocyte precursor cells (OPCs) are thought to maintain homeostasis and contribute
to long-term repair in adult white matter; however, their roles in the acute phase after brain …

Exclusively neuron-centric approaches to neuropathological mechanisms have not resulted
in major new breakthroughs in the prevention and therapy of neurodegenerative diseases …

Before the roles of normal, mature astrocytes in the mammalian CNS can be discussed, we
first need to define these cells. A definition proposed here is that such a class is best defined …

The molecular mechanisms that govern the maturation of oligodendrocyte lineage cells
remain unclear. Emerging studies have shown that N 6-methyladenosine (m 6 A), the most …