Quinolizidine-type alkaloids: chemodiversity, occurrence, and bioactivity
W Cely-Veloza, MJ Kato, E Coy-Barrera - ACS omega, 2023 - ACS Publications
Quinolizidine alkaloids (QAs) are nitrogen-containing compounds produced naturally as
specialized metabolites distributed in plants and animals (eg, frogs, sponges). The present …
specialized metabolites distributed in plants and animals (eg, frogs, sponges). The present …
An Asymmetric Hydrogenation/N‐Alkylation Sequence for a Step‐Economical Route to Indolizidines and Quinolizidines
W Zhao, W Wang, H Zhou, Q Liu, Z Ma… - Angewandte Chemie …, 2023 - Wiley Online Library
The direct catalytic asymmetric hydrogenation of pyridines for the synthesis of piperidines
remains a challenge. Herein, we report a one‐pot asymmetric hydrogenation of pyridines …
remains a challenge. Herein, we report a one‐pot asymmetric hydrogenation of pyridines …
Anti-inflammatory efficacy and relevant SAR investigations of novel chiral pyrazolo isoquinoline derivatives: Design, synthesis, in-vitro, in-vivo, and computational …
M Akhtar, J Niu, Y Zhu, Z Luo, T Tian, Y Dong… - European Journal of …, 2023 - Elsevier
Isoquinoline alkaloids are a rich source of multimodal agents with distinctive structural
specificity and various pharmacological activities. In the present report, we propose a …
specificity and various pharmacological activities. In the present report, we propose a …
Emerging functions within the enzyme families of plant alkaloid biosynthesis
F Muro-Villanueva, RS Nett - Phytochemistry Reviews, 2023 - Springer
The alkaloids are a major class of nitrogen-containing plant specialized metabolites that
function as both toxic defense compounds and useful pharmaceuticals. Understanding the …
function as both toxic defense compounds and useful pharmaceuticals. Understanding the …
Attenuating Colorectal Cancer Using Nine Cultivars of Australian Lupin Seeds: Apoptosis Induction Triggered by Mitochondrial Reactive Oxygen Species Generation …
As Australian lupin cultivars are rich sources of polyphenols, dietary fibers, high-quality
proteins, and abundant bioactive compounds with significant antioxidant, antidiabetic, and …
proteins, and abundant bioactive compounds with significant antioxidant, antidiabetic, and …
New Analytical Approach to Quinolizidine Alkaloids and Their Assumed Biosynthesis Pathways in Lupin Seeds
Alkaloids play an essential role in protecting plants against herbivores. Humans can also
benefit from the pharmacological effects of these compounds. Plants produce an immense …
benefit from the pharmacological effects of these compounds. Plants produce an immense …
Deciphering Alkaloid and Flavonoid Biosynthesis in Different Tissues of Sophora tonkinensis via Transcriptomics and Metabolomics
Y Liang, G Wei, X Liang, M Tang, H He, D Tang, Y Lin… - 2024 - researchsquare.com
Background: Sophora tonkinensis Gagnep is an important Chinese herbal medicine, with
alkaloids and flavonoids being the primary pharmacological substances. However …
alkaloids and flavonoids being the primary pharmacological substances. However …
Synthesis of an alkaloid inspired compound collection
R Yao - 2022 - orbit.dtu.dk
Pseudo-natural products, defined as the non-biogenic fusion of natural product fragments,
have emerged as an inspiration for rapidly identifying novel biologically active molecules …
have emerged as an inspiration for rapidly identifying novel biologically active molecules …