Antibiotic resistance in Pakistan: a systematic review of past decade

H Bilal, MN Khan, T Rehman, MF Hameed… - BMC infectious …, 2021 - Springer
Background During the last six decades, extensive use of antibiotics has selected resistant
strains, increasing the rate of fatal infectious diseases, and exerting an economic burden on …

Global Prevalence of Nosocomial Multidrug-Resistant Klebsiella pneumoniae: A Systematic Review and Meta-Analysis

NA Mohd Asri, S Ahmad, R Mohamud, N Mohd Hanafi… - Antibiotics, 2021 - mdpi.com
The emergence of nosocomial multidrug-resistant Klebsiella pneumoniae is an escalating
public health threat worldwide. The prevalence of nosocomial infections due to K …

Distribution of blaCTX − M, blaTEM, blaSHV and blaOXA genes in Extended-spectrum-β-lactamase-producing Clinical isolates: A three-year multi …

S Abrar, NU Ain, H Liaqat, S Hussain… - … Resistance & Infection …, 2019 - Springer
Background Frequency of extended-spectrum-β-lactamase-producing clinical isolates is
increasing worldwide. This is a multi-center study which was aimed to check the frequency …

Prevalence of multidrug-resistant and extended-spectrum beta-lactamase producing Gram-negative isolates from clinical samples in a tertiary care hospital of Nepal

A Shilpakar, M Ansari, KR Rai, G Rai… - Tropical Medicine and …, 2021 - Springer
Background The existence of multidrug-resistant organisms, including extended-spectrum
beta-lactamases (ESBLs), is on rise across the globe and is becoming a severe problem …

Antimicrobial susceptibility and clinical characteristics of multidrug-resistant polymicrobial infections in Pakistan, a retrospective study 2019–2021

MU Qamar, M Rizwan, R Uppal, AA Khan… - Future …, 2023 - Future Medicine
Background: We determined the prevalence of antimicrobial resistance (AMR) in
polymicrobial pathogens in Pakistan. Methods: A total of 70,518 clinical samples were …

A high prevalence of multi-drug resistant Gram-negative bacilli in a Nepali tertiary care hospital and associated widespread distribution of Extended-Spectrum Beta …

S Manandhar, RM Zellweger, N Maharjan… - Annals of clinical …, 2020 - Springer
Background Multi-drug resistance (MDR) and extensive-drug resistance (XDR) associated
with extended-spectrum beta-lactamases (ESBLs) and carbapenemases in Gram-negative …

Impact of antimicrobial stewardship on antibiogram, consumption and incidence of multi drug resistance

RM Darwish, SG Matar, AAA Snaineh… - BMC Infectious …, 2022 - Springer
Introduction Antimicrobial stewardship programs are intended to improve patient outcomes,
reduce side effects, bacterial resistance, and costs. Thus, it is important to assess their …

Discovery of beta-lactamase CMY-10 inhibitors for combination therapy against multi-drug resistant Enterobacteriaceae

N Parvaiz, F Ahmad, W Yu, AD MacKerell Jr… - PLoS One, 2021 - journals.plos.org
β-lactam antibiotics are the most widely used antimicrobial agents since the discovery of
benzylpenicillin in the 1920s. Unfortunately, these life-saving antibiotics are vulnerable to …

Molecular Epidemiology of mcr-1, blaKPC-2, and blaNDM-1 Harboring Clinically Isolated Escherichia coli from Pakistan

H Bilal, TU Rehman, MA Khan, F Hameed… - Infection and Drug …, 2021 - Taylor & Francis
Purpose The multiple-drug resistant Escherichia coli are among the deadliest pathogens
causing life-threatening infections. This study was planned to determine the molecular …

Understanding of future prescribers about antimicrobial resistance and their preparedness towards antimicrobial stewardship activities in Pakistan: Findings and …

K Hayat, N Fatima, MF Umer, FU Khan… - Frontiers in …, 2022 - frontiersin.org
Background: Insufficient antimicrobial-related training for physicians during their
undergraduate education could have a negative impact on their prescribing. Unlike previous …