Cognitive and behavioural flexibility: neural mechanisms and clinical considerations
LQ Uddin - Nature Reviews Neuroscience, 2021 - nature.com
Cognitive and behavioural flexibility permit the appropriate adjustment of thoughts and
behaviours in response to changing environmental demands. Brain mechanisms enabling …
behaviours in response to changing environmental demands. Brain mechanisms enabling …
Bring the noise: reconceptualizing spontaneous neural activity
LQ Uddin - Trends in Cognitive Sciences, 2020 - cell.com
Definitions of what constitutes the 'signal of interest'in neuroscience can be controversial,
due in part to continuously evolving notions regarding the significance of spontaneous …
due in part to continuously evolving notions regarding the significance of spontaneous …
The older adult brain is less modular, more integrated, and less efficient at rest: A systematic review of large‐scale resting‐state functional brain networks in aging
The literature on large‐scale resting‐state functional brain networks across the adult
lifespan was systematically reviewed. Studies published between 1986 and July 2021 were …
lifespan was systematically reviewed. Studies published between 1986 and July 2021 were …
Brain dynamics underlying cognitive flexibility across the lifespan
L Kupis, ZT Goodman, S Kornfeld, S Hoang… - Cerebral …, 2021 - academic.oup.com
The neural mechanisms contributing to flexible cognition and behavior and how they
change with development and aging are incompletely understood. The current study …
change with development and aging are incompletely understood. The current study …
The potential of blood neurofilament light as a marker of neurodegeneration for Alzheimer's disease
Y Jung, JS Damoiseaux - Brain, 2024 - academic.oup.com
Over the past several years, there has been a surge in blood biomarker studies examining
the value of plasma or serum neurofilament light (NfL) as a biomarker of neurodegeneration …
the value of plasma or serum neurofilament light (NfL) as a biomarker of neurodegeneration …
Behavior needs neural variability
Human and non-human animal behavior is highly malleable and adapts successfully to
internal and external demands. Such behavioral success stands in striking contrast to the …
internal and external demands. Such behavioral success stands in striking contrast to the …
Endless fluctuations: temporal dynamics of the amplitude of low frequency fluctuations
Intrinsic neural activity ubiquitously persists in all physiological states. However, how
intrinsic brain activity (iBA) changes over a short time remains unknown. To uncover the …
intrinsic brain activity (iBA) changes over a short time remains unknown. To uncover the …
Developmental neuroimaging of cognitive flexibility: update and future directions
Cognitive flexibility, or the ability to mentally switch between tasks according to changing
environmental demands, supports optimal life outcomes, making it an important executive …
environmental demands, supports optimal life outcomes, making it an important executive …
Dopamine signaling modulates the stability and integration of intrinsic brain networks
Dopaminergic projections are hypothesized to stabilize neural signaling and neural
representations, but how they shape regional information processing and large-scale …
representations, but how they shape regional information processing and large-scale …
Childhood stress, grown-up brain networks: corticolimbic correlates of threat-related early life stress and adult stress response
BackgroundExposure to threat-related early life stress (ELS) has been related to
vulnerability for stress-related disorders in adulthood, putatively via disrupted corticolimbic …
vulnerability for stress-related disorders in adulthood, putatively via disrupted corticolimbic …