Frailty syndrome: implications and challenges for health care policy
G Kojima, AEM Liljas, S Iliffe - Risk management and healthcare …, 2019 - Taylor & Francis
Older adults are a highly heterogeneous group with variable health and functional life
courses. Frailty has received increasing scientific attention as a potential explanation of the …
courses. Frailty has received increasing scientific attention as a potential explanation of the …
Oncologic emergencies and urgencies: A comprehensive review
BE Gould Rothberg, TE Quest… - CA: a cancer journal …, 2022 - Wiley Online Library
Patients with advanced cancer generate 4 million visits annually to emergency departments
(EDs) and other dedicated, high‐acuity oncology urgent care centers. Because of both the …
(EDs) and other dedicated, high‐acuity oncology urgent care centers. Because of both the …
Frailty index and all-cause and cause-specific mortality in Chinese adults: a prospective cohort study
Background The fraily index is a useful proxy measure of accelerated biological ageing and
in estimating all-cause and cause-specific mortality in older individuals in European and US …
in estimating all-cause and cause-specific mortality in older individuals in European and US …
Frailty and cancer: current perspectives on assessment and monitoring
V Goede - Clinical interventions in aging, 2023 - Taylor & Francis
Frailty, an age-related condition of increased vulnerability to acute endogenous or
exogenous stressors, is a key barrier to successful treatment of cancer in older people. In …
exogenous stressors, is a key barrier to successful treatment of cancer in older people. In …
Cancer and aging: two tightly interconnected biological processes
L Berben, G Floris, H Wildiers, S Hatse - Cancers, 2021 - mdpi.com
Simple Summary As life expectancy is increasing, the older population is rapidly growing.
However, older patients with cancer are still underrepresented in clinical trials, making …
However, older patients with cancer are still underrepresented in clinical trials, making …
Sarcopenia and postoperative complication risk in gastrointestinal surgical oncology: a meta-analysis
C Simonsen, P de Heer, ED Bjerre, C Suetta… - Annals of …, 2018 - journals.lww.com
Objective: The aim of the study was to evaluate sarcopenia as a predictor of postoperative
risk of major and total complications after surgery for gastrointestinal cancer. Background …
risk of major and total complications after surgery for gastrointestinal cancer. Background …
EHRA expert consensus document on the management of arrhythmias in frailty syndrome, endorsed by the heart rhythm society (HRS), Asia Pacific heart rhythm …
I Savelieva, S Fumagalli, RA Kenny, S Anker… - Europace, 2023 - academic.oup.com
There is an increasing proportion of the general population surviving to old age with
significant chronic disease, multi-morbidity, and disability. The prevalence of pre-frail state …
significant chronic disease, multi-morbidity, and disability. The prevalence of pre-frail state …
Irradiated tumor cell–derived microparticles mediate tumor eradication via cell killing and immune reprogramming
C Wan, Y Sun, Y Tian, L Lu, X Dai, J Meng, J Huang… - Science …, 2020 - science.org
Radiotherapy (RT) is routinely used in cancer treatment, but expansion of its clinical
indications remains challenging. The mechanism underlying the radiation-induced …
indications remains challenging. The mechanism underlying the radiation-induced …
Long non-coding RNAs regulate drug resistance in cancer
Chemoresistance, whether intrinsic or acquired, is a major obstacle in the treatment of
cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various …
cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various …
Defining undertreatment and overtreatment in older adults with cancer: a scoping literature review
PURPOSE The terms undertreatment and overtreatment are often used to describe
inappropriate management of older adults with cancer. We conducted a comprehensive …
inappropriate management of older adults with cancer. We conducted a comprehensive …