Older adults are a highly heterogeneous group with variable health and functional life
courses. Frailty has received increasing scientific attention as a potential explanation of the …

Patients with advanced cancer generate 4 million visits annually to emergency departments
(EDs) and other dedicated, high‐acuity oncology urgent care centers. Because of both the …

Background The fraily index is a useful proxy measure of accelerated biological ageing and
in estimating all-cause and cause-specific mortality in older individuals in European and US …

Frailty, an age-related condition of increased vulnerability to acute endogenous or
exogenous stressors, is a key barrier to successful treatment of cancer in older people. In …

Simple Summary As life expectancy is increasing, the older population is rapidly growing.
However, older patients with cancer are still underrepresented in clinical trials, making …

Objective: The aim of the study was to evaluate sarcopenia as a predictor of postoperative
risk of major and total complications after surgery for gastrointestinal cancer. Background …

There is an increasing proportion of the general population surviving to old age with
significant chronic disease, multi-morbidity, and disability. The prevalence of pre-frail state …

Radiotherapy (RT) is routinely used in cancer treatment, but expansion of its clinical
indications remains challenging. The mechanism underlying the radiation-induced …

Chemoresistance, whether intrinsic or acquired, is a major obstacle in the treatment of
cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various …

PURPOSE The terms undertreatment and overtreatment are often used to describe
inappropriate management of older adults with cancer. We conducted a comprehensive …