Microsatellite instability is a well‐recognised phenomenon. Ten to 15% of sporadic
colorectal cancers with a high level of MSI form a well defined group with distinct …

Colorectal cancer (CRC) is the third most frequently diagnosed cancer in the world. For a
long time, only one pathway of colorectal carcinogenesis was known. In recent years, a new …

Patients with hyperplastic polyposis have multiple hyperplastic polyps (HPs) and increased
risk of colorectal carcinomas. Aberrant crypt foci (ACF) are postulated to be the earliest …

OBJECTIVES: Hyperplastic polyposis (HP) is a poorly understood condition. The aim of this
study is to describe the phenotype and the risk of cancer in HP. METHODS: Patients with …

The non‐inherited gastrointestinal polyposis syndromes represent a group of rare disorders
characterized by the presence of multiple, non‐adenomatous polyps on the gastrointestinal …

The colorectal polyposes are uncommon and frequently present diagnostic difficulties.
Although the final diagnostic arbiter is the demonstration of a germline mutation, this may not …

The mutated in colorectal cancer (MCC) gene is in close linkage with the adenomatous
polyposis coli (APC) gene on chromosome 5, in a region of frequent loss of heterozygosity in …

This Internet-based quiz (http://kathrin. unibas. ch/polyp/) tested the diagnostic variability of
168 pathologists in the diagnosis of 20 colorectal polyps on 3 representative images …

Several studies have raised warnings about the limited effectiveness of colonoscopy for the
prevention of colorectal cancer (CRC), especially of the proximal colon. Two major …

Background and aims: Colorectal adenomas are recognised as precursors of colorectal
carcinomas. The significance of hyperplastic (metaplastic) colorectal polyps is unknown. The …