Intracellular G-actin targeting of peripheral sensory neurons by the multifunctional engineered protein C2C confers relief from inflammatory pain
D Allen, Y Zhou, A Wilhelm, P Blum - Scientific reports, 2020 - nature.com
The engineered multifunctional protein C2C was tested for control of sensory neuron activity
by targeted G-actin modification. C2C consists of the heptameric oligomer, C2II-CI, and the …
by targeted G-actin modification. C2C consists of the heptameric oligomer, C2II-CI, and the …
Mechanisms controlling the trafficking, localization, and abundance of presynaptic Ca 2 channels
KL Cunningham, JT Littleton - 2023 - europepmc.org
Abstract Voltage-gated Ca 2+ channels (VGCCs) mediate Ca 2+ influx to trigger
neurotransmitter release at specialized presynaptic sites termed active zones (AZs). The …
neurotransmitter release at specialized presynaptic sites termed active zones (AZs). The …
Role of L-Type Ca2+ Channels in Sensory Cells
A Koschak, A Pinggera, K Schicker… - Pathologies of Calcium …, 2014 - Springer
L-type Ca 2+ channels play an important role in sensory cells present in the inner ear and
the retina. Ca v 1.3 predominates in sensory cells of the inner ear (inner and outer cochlear …
the retina. Ca v 1.3 predominates in sensory cells of the inner ear (inner and outer cochlear …
[PDF][PDF] The Ca2+ channel subunit CaVβ2a down-regulates voltage-activated ion current densities by disrupting actin-dependent traffic in chromaffin cells
MJ Guerra, AM González-Jamett, X Báez-Matus… - academia.edu
ABSTRACT β-subunits of the Ca2+ channel have been conventionally regarded as auxiliary
subunits that regulate the expression and activity of the pore-forming α1 subunit. However …
subunits that regulate the expression and activity of the pore-forming α1 subunit. However …
Tracking quantum dot–tagged calcium channels at vertebrate photoreceptor synapses: retinal slices and dissociated cells
AJ Mercer, WB Thoreson - Current Protocols in Neuroscience, 2013 - Wiley Online Library
At synapses in the central nervous system, precisely localized assemblies of presynaptic
proteins, neurotransmitter‐filled vesicles, and postsynaptic receptors are required to …
proteins, neurotransmitter‐filled vesicles, and postsynaptic receptors are required to …
[PDF][PDF] Localization of Cav1. 3 L-type calcium channels in the mouse retina
C Kugler - phaidra.univie.ac.at
The bivalent calcium ion (Ca2+) is an important intracellular messenger acting upon and
regulating various cellular processes. The intracellular concentration of Ca2+,[Ca2+] i, lies at …
regulating various cellular processes. The intracellular concentration of Ca2+,[Ca2+] i, lies at …
[PDF][PDF] Regulation of presynaptic strength by controlling Ca2+ channel mobility: Effects of cholesterol depletion on release at...
MATERIALS AND METHODS Animal care and use. Experimental procedures were
approved by the University of Nebraska Medical Center Institutional Animal Care and Use …
approved by the University of Nebraska Medical Center Institutional Animal Care and Use …
L'organisation spatiale des canaux calciques cav1. 3 détermine l'efficacité de l'exocytose des synapses à ruban dans les cellules ciliées de l'oreille interne
P Vincent - 2015 - theses.hal.science
Les cellules ciliées internes (CCIs) de la cochlée encodent les signaux acoustiques en
impulsions électriques au niveau des synapses à ruban formées avec les fibres afférentes …
impulsions électriques au niveau des synapses à ruban formées avec les fibres afférentes …
Nanoscale Components of Neurons: From Biomolecules to Nanodevices
NJ Woolf, A Priel, JA Tuszynski, NJ Woolf… - … and Functional Roles of …, 2010 - Springer
Neurons contain many structurally diverse nanoscale components, which individually carry
out a well–defined function, or as is increasingly found to be the case, multiple functions …
out a well–defined function, or as is increasingly found to be the case, multiple functions …
[图书][B] Mouse model for muscle specific kinase (MUSK)-induced myasthenia gravis, and, Direct protein interactions modulate the gating and trafficking of large …
S Jha - 2008 - search.proquest.com
Abstract PART 1. Myasthenia gravis (MG) is a disease of the neuromuscular junction. It is
caused by anti-acetylcholine receptor (AChR) auto-antibodies. AChR antibodies are …
caused by anti-acetylcholine receptor (AChR) auto-antibodies. AChR antibodies are …