Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy
TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical Reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Recent progress in photosensitizers for overcoming the challenges of photodynamic therapy: from molecular design to application
Photodynamic therapy (PDT), a therapeutic mode involving light triggering, has been
recognized as an attractive oncotherapy treatment. However, nonnegligible challenges …
recognized as an attractive oncotherapy treatment. However, nonnegligible challenges …
Nanostructured phthalocyanine assemblies with efficient synergistic effect of type I photoreaction and photothermal action to overcome tumor hypoxia in photodynamic …
YY Zhao, L Zhang, Z Chen, BY Zheng… - Journal of the …, 2021 - ACS Publications
Most photodynamic therapy (PDT) paradigms work through the highly O2-dependent type II
photoreaction to generate singlet oxygen (1O2). The hypoxic microenvironment of solid …
photoreaction to generate singlet oxygen (1O2). The hypoxic microenvironment of solid …
Phthalocyanines as medicinal photosensitizers: Developments in the last five years
X Li, BD Zheng, XH Peng, SZ Li, JW Ying… - Coordination Chemistry …, 2019 - Elsevier
Owing to their high extinction coefficients, long absorption wavelengths, and modification
tunable photophysical and photochemical properties, phthalocyanines (Pcs) have been …
tunable photophysical and photochemical properties, phthalocyanines (Pcs) have been …
Nanotherapeutic intervention in photodynamic therapy for cancer
The clinical need for photodynamic therapy (PDT) has been growing for several decades.
Notably, PDT is often used in oncology to treat a variety of tumors since it is a low-risk …
Notably, PDT is often used in oncology to treat a variety of tumors since it is a low-risk …
Conjugates of porphyrinoid-based photosensitizers with cytotoxic drugs: current progress and future directions toward selective photodynamic therapy
VF Otvagin, NS Kuzmina, ES Kudriashova… - Journal of medicinal …, 2022 - ACS Publications
Photodynamic therapy (PDT) is a treatment modality where light-mediated activation of
photosensitizers in a patient's body leads to the generation of cytotoxic reactive oxygen …
photosensitizers in a patient's body leads to the generation of cytotoxic reactive oxygen …
[HTML][HTML] Molecular targeting of epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor (VEGFR)
Epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor
(VEGFR) are two extensively studied membrane-bound receptor tyrosine kinase proteins …
(VEGFR) are two extensively studied membrane-bound receptor tyrosine kinase proteins …
Synthesis and anticancer mechanisms of zinc (II)-8-hydroxyquinoline complexes with 1, 10-phenanthroline ancillary ligands
LQ Du, TY Zhang, XM Huang, Y Xu, MX Tan… - Dalton …, 2023 - pubs.rsc.org
Twenty new zinc (II) complexes with 8-hydroxyquinoline (H-Q1–H-Q6) in the presence of 1,
10-phenanthroline derivatives (D1–D10) were synthesized and formulated as [Zn (Q1) 2 …
10-phenanthroline derivatives (D1–D10) were synthesized and formulated as [Zn (Q1) 2 …
[HTML][HTML] EGFR-targeted photodynamic therapy
L Ulfo, PE Costantini, M Di Giosia, A Danielli… - Pharmaceutics, 2022 - mdpi.com
The epidermal growth factor receptor (EGFR) plays a pivotal role in the proliferation and
metastatization of cancer cells. Aberrancies in the expression and activation of EGFR are …
metastatization of cancer cells. Aberrancies in the expression and activation of EGFR are …
Complexes of Zn (II) with a mixed tryptanthrin derivative and curcumin chelating ligands as new promising anticancer agents
ZF Wang, QX Nong, HL Yu, QP Qin, FH Pan… - Dalton …, 2022 - pubs.rsc.org
In this study, two novel curcumin (H-Cur)–tryptanthrin metal compounds—[Zn (TA) Cl2], ie,
Zn (TA), and [Zn (TA)(Cur)] Cl, ie, Zn (TAC)—were synthesized and investigated using 5-(bis …
Zn (TA), and [Zn (TA)(Cur)] Cl, ie, Zn (TAC)—were synthesized and investigated using 5-(bis …