An Erlotinib triphenylphosphane gold (I) conjugate has been prepared from AuCl (PPh 3)
and its crystal structure has been established by X-ray diffraction, showing a metallo-helicate …

The outcome of molecular targeted therapies is restricted by the ambiguous molecular
subtypes of nonsmall cell lung cancer (NSCLC), which are difficult to be defined with …

Zinc (II) phthalocyanines are favorable candidates as photosensitizers (PSs) for
photodynamic therapy (PDT). However, zinc (II) phthalocyanines also suffer from poor water …

Aberrant expression of the epidermal growth factor receptor (EGFR) is a common
characteristic of many cancers, including non–small cell lung carcinoma (NSCLC), head and …

The combined use of a photosensitizing agent, light and dioxygen for the treatment of
diseases has become known as photodynamic therapy (PDT) and was first discovered more …

Benefited from the high orientation of coordinated interaction, metallo-supramolecular
materials have attracted enormous interest in many fields. Herein, a novel metallo …

Photodynamic therapy (PDT) is now in clinical practice in many European and American
countries as a minimally invasive therapeutic technique to treat oncologic malignancies and …

Dasatinib is a kinase-targeted drug used in the treatment of leukemia. Regrettably, it
remains far from optimal medicine due to insurmountable drug resistance and side effects …

In the solid state each of three binuclear zinc dithiocarbamates bearing hydroxyethyl
groups,{Zn [S 2 CN (R) CH 2 CH 2 OH] 2} 2 for R= iPr (1), CH 2 CH 2 OH (2), and Me (3) …

It is urgently required to develop the molecular agents with high therapeutic efficacy and low
side effects for precise cancer therapy. Herein, an advanced multifunctional prodrug B-BDP …