Exploration of photophysical and photochemical properties of Zinc phthalocyanine-loaded SDC/TPGS mixed micelles

X Lu, W Zhu, T Chen, Q Peng, C Yu, M Yang - Chemical Physics Letters, 2019 - Elsevier
A novel mixed micelles was developed to improve the solubility of Zinc phthalocyanine
(ZnPc). Sodium deoxycholate (SDC) and D-alpha tocopheryl polyethylene glycol succinate …

68Ga labeled Erlotinib: A novel PET probe for imaging EGFR over-expressing tumors

A Jain, M Kameswaran, U Pandey, K Prabhash… - Bioorganic & medicinal …, 2017 - Elsevier
Molecular imaging using radiolabeled Tyrosine Kinase Inhibitors (TKI) is a promising
strategy for detection and staging of EGFR-positive cancers. A novel analogue of one such …

AH2O2-Responsive Boron Dipyrromethene-Based Photosensitizer for Imaging-Guided Photodynamic Therapy

ZW Wang, D Su, XQ Li, JJ Cao, DC Yang, JY Liu - Molecules, 2018 - mdpi.com
In this study, we demonstrate a novel H2O2 activatable photosensitizer (compound 7) which
contains a diiodo distyryl boron dipyrromethene (BODIPY) core and an arylboronate group …

Three-in-one erlotinib-modified NIR photosensitizer for fluorescence imaging and synergistic chemo-photodynamic therapy

D Liu, Y Li, H Zhang, B Wang, C Yao, M Lan… - Chinese Chemical …, 2024 - Elsevier
Photodynamic therapy (PDT) presents a promising avenue in cancer treatment. Erlotinib, an
FDA-approved anticancer drug targeting epidermal growth factor receptor (EGFR), has …

In vitro photodynamic activities of zinc (II) phthalocyanines substituted with pyridine moieties

JY Liu, J Li, X Yuan, WM Wang, JP Xue - … and photodynamic therapy, 2016 - Elsevier
In vitro photodynamic activities of zinc(II) phthalocyanines substituted with pyridine moieties -
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Improved photodynamic anticancer activity and mechanisms of a promising zinc (II) phthalocyanine-quinoline conjugate photosensitizer in vitro and in vivo

J Chen, Y Wang, Y Fang, Z Jiang, A Wang… - Biomedical Optics …, 2020 - opg.optica.org
Since the discovery of photodynamic therapy, scientists have constantly been searching for
more effective and ideal photosensitizers (PSs). As part of our ongoing interest in the …

Epidermal growth factor receptor-targeted delivery of a singlet-oxygen sensitizer with thermal controlled release for efficient anticancer therapy

J Chen, D Li, B Huo, F Zhang, X Zhao… - Molecular …, 2019 - ACS Publications
Photodynamic therapy (PDT) utilizing light-induced singlet oxygen has achieved attractive
results in anticancer fields; however, its development is hindered by limited light penetration …

Small molecular target-based multifunctional upconversion nanocomposites for targeted and in-depth photodynamic and chemo-anticancer therapy

X Jia, HN Ye, H Weng, N Huang, Y Yu… - Materials Science and …, 2019 - Elsevier
A novel multifunctional nano-system, ZnPc-UCNPs-PEG-G, was designed for targeted and
in-depth photodynamic therapy. The nano-system was built via covalent conjugation, in …

Silicon Phthalocyanines Axially Disubstituted with Erlotinib toward Small‐Molecular‐Target‐Based Photodynamic Therapy

JJ Chen, YZ Huang, MR Song, ZH Zhang… - …, 2017 - Wiley Online Library
Small‐molecular‐target‐based photodynamic therapy—a promising targeted anticancer
strategy—was developed by conjugating zinc (II) phthalocyanine with a small‐molecular …

Preparation and in vitro photodynamic activity of glucosylated zinc (II) phthalocyanines as underlying targeting photosensitizers

JY Liu, C Wang, CH Zhu, ZH Zhang, JP Xue - Molecules, 2017 - mdpi.com
Two novel glucosylated zinc (II) phthalocyanines 7a–7b, as well as the acetyl-protected
counterparts 6a–6b, have been synthesized by the Cu (I)-catalyzed 1, 3-dipolar …