Prostate cancer has the highest prevalence of any nonskin cancer in the human body, with
similar likelihood of neoplastic foci found within the prostates of men around the world …

BACKGROUND The widespread use of prostate‐specific antigen (PSA) screening has had
a tremendous impact on all aspects of the management of prostate carcinoma. Although …

Background Recent observations suggest that prostate cancer is an increasing disease
among older adolescents and young adults. Methods Incidence, mortality, and survival data …

BACKGROUND: Outcomes of treatment for young men compared with older men with
prostate cancer are poorly defined outside of limited institutional series. In this study, the …

BACKGROUND A family history of prostate cancer (PCa) or breast cancer (BCa) has been
associated with the risk of PCa, but the risks were inconsistent in terms of the affected family …

Background Little is known about predictors of prostate cancer severity in young men.
Therefore, we examined whether family history and obesity influence risk of high‐grade …

In recent years, the incidence of cancers is continuously increasing in young adults. Early-
onset cancer (EOC) is usually defined as patients with cancers under the age of 50, and may …

Genetic factors and their inter-actions with environmental conditions and internal
microenvironment influence the prostate cancer (PC) development, so that gene expression …

Purpose ERG expression has been proposed to signify molecular subtype of PCA. However,
its significance in early onset prostate cancer (PCA) is not characterized. Materials and …

Purpose While a family history (FH) of prostate cancer represents an established risk factor
for prostate cancer diagnosis, conflicting data exist regarding the oncologic importance of …