Motile ciliopathies

J Wallmeier, KG Nielsen, CE Kuehni… - Nature reviews Disease …, 2020 - nature.com
Motile cilia are highly complex hair-like organelles of epithelial cells lining the surface of
various organ systems. Genetic mutations (usually with autosomal recessive inheritance) …

Inhaled corticosteroids in COPD: friend or foe?

A Agusti, LM Fabbri, D Singh, J Vestbo… - European …, 2018 - Eur Respiratory Soc
The efficacy, safety and positioning of inhaled corticosteroids (ICS) in the treatment of
patients with chronic obstructive pulmonary disease (COPD) is much debated, since it can …

Risk of fractures with inhaled corticosteroids in COPD: systematic review and meta-analysis of randomised controlled trials and observational studies

YK Loke, R Cavallazzi, S Singh - Thorax, 2011 - thorax.bmj.com
Background The effect of inhaled corticosteroids (ICS) on fracture risk in patients with
chronic obstructive pulmonary disease (COPD) remains uncertain. The aim of this study was …

Long-term use of inhaled corticosteroids and the risk of pneumonia in chronic obstructive pulmonary disease: a meta-analysis

S Singh, AV Amin, YK Loke - Archives of internal medicine, 2009 - jamanetwork.com
Background Recent studies have suggested a possible association between pneumonia
and the use of inhaled corticosteroids. We aimed to ascertain the risk of pneumonia with …

Pneumonia and pneumonia related mortality in patients with COPD treated with fixed combinations of inhaled corticosteroid and long acting β2 agonist: observational …

C Janson, K Larsson, KH Lisspers, B Ställberg… - Bmj, 2013 - bmj.com
Objective To investigate the occurrence of pneumonia and pneumonia related events in
patients with chronic obstructive pulmonary disease (COPD) treated with two different fixed …

Use of inhaled corticosteroids and the risk of tuberculosis

CH Lee, K Kim, MK Hyun, EJ Jang, NR Lee, JJ Yim - Thorax, 2013 - thorax.bmj.com
Background Inhaled corticosteroid (ICS) use could decrease local immunity of the lung.
Concerns have been raised regarding the risk of tuberculosis (TB) development among ICS …

Impact of exacerbations on health care cost and resource utilization in chronic obstructive pulmonary disease patients with chronic bronchitis from a predominantly …

MK Pasquale, SX Sun, F Song, HJ Hartnett… - … journal of chronic …, 2012 - Taylor & Francis
Background Exacerbations of chronic obstructive pulmonary disease (COPD) lead to
significant increases in resource utilization and cost to the health care system. COPD …

Nanotechnology based advanced therapeutic strategies for targeting interleukins in chronic respiratory diseases

MS Hussain, P Sharma, DS Dhanjal, N Khurana… - Chemico-biological …, 2021 - Elsevier
Both communicable and non-communicable chronic respiratory conditions have accorded
for suffering of millions of people of all ages and stated to be leading cause of death …

[HTML][HTML] Inhaled drugs to reduce exacerbations in patients with chronic obstructive pulmonary disease: a network meta-analysis

MA Puhan, LM Bachmann, J Kleijnen, G Ter Riet… - BMC medicine, 2009 - Springer
Background Most patients with chronic obstructive pulmonary disease (COPD) receive
inhaled long-acting bronchodilators and inhaled corticosteroids. Conventional meta …

Long-term use of inhaled corticosteroids in COPD and the risk of fracture

AV Gonzalez, J Coulombe, P Ernst, S Suissa - Chest, 2018 - Elsevier
Background It is uncertain whether long-term use of inhaled corticosteroids (ICSs), widely
used to treat COPD, increases the risk of fracture, particularly in women, in view of the …