Imaging faster neural dynamics with fast fMRI: A need for updated models of the hemodynamic response
JR Polimeni, LD Lewis - Progress in neurobiology, 2021 - Elsevier
Fast fMRI enables the detection of neural dynamics over timescales of hundreds of
milliseconds, suggesting it may provide a new avenue for studying subsecond neural …
milliseconds, suggesting it may provide a new avenue for studying subsecond neural …
Cerebrospinal fluid mechanics and its coupling to cerebrovascular dynamics
AA Linninger, K Tangen, CY Hsu… - Annual Review of Fluid …, 2016 - annualreviews.org
Cerebrospinal fluid (CSF) is not stagnant but displays fascinating oscillatory flow patterns
inside the ventricular system and reversing fluid exchange between the cranial vault and …
inside the ventricular system and reversing fluid exchange between the cranial vault and …
The capillary bed offers the largest hemodynamic resistance to the cortical blood supply
IG Gould, P Tsai, D Kleinfeld… - Journal of Cerebral …, 2017 - journals.sagepub.com
The cortical angioarchitecture is a key factor in controlling cerebral blood flow and oxygen
metabolism. Difficulties in imaging the complex microanatomy of the cortex have so far …
metabolism. Difficulties in imaging the complex microanatomy of the cortex have so far …
[PDF][PDF] Brain microvasculature has a common topology with local differences in geometry that match metabolic load
The microvasculature underlies the supply networks that support neuronal activity within
heterogeneous brain regions. What are common versus heterogeneous aspects of the …
heterogeneous brain regions. What are common versus heterogeneous aspects of the …
Mapping oxygen concentration in the awake mouse brain
DG Lyons, A Parpaleix, M Roche, S Charpak - Elife, 2016 - elifesciences.org
Although critical for brain function, the physiological values of cerebral oxygen concentration
have remained elusive because high-resolution measurements have only been performed …
have remained elusive because high-resolution measurements have only been performed …
Multiscale modelling of blood flow in cerebral microcirculation: Details at capillary scale control accuracy at the level of the cortex
M Peyrounette, Y Davit, M Quintard, S Lorthois - PloS one, 2018 - journals.plos.org
Aging or cerebral diseases may induce architectural modifications in human brain
microvascular networks, such as capillary rarefaction. Such modifications limit blood and …
microvascular networks, such as capillary rarefaction. Such modifications limit blood and …
More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction
Our understanding of how capillary blood flow and oxygen distribute across cortical layers to
meet the local metabolic demand is incomplete. We addressed this question by using two …
meet the local metabolic demand is incomplete. We addressed this question by using two …
[HTML][HTML] Analysis of red blood cell partitioning at bifurcations in simulated microvascular networks
Partitioning of red blood cells (RBCs) at vascular bifurcations has been studied over many
decades using in vivo, in vitro, and theoretical models. These studies have shown that RBCs …
decades using in vivo, in vitro, and theoretical models. These studies have shown that RBCs …
Methods to label, image, and analyze the complex structural architectures of microvascular networks
Microvascular networks play key roles in oxygen transport and nutrient delivery to meet the
varied and dynamic metabolic needs of different tissues throughout the body, and their …
varied and dynamic metabolic needs of different tissues throughout the body, and their …
Adaptive constrained constructive optimisation for complex vascularisation processes
Mimicking angiogenetic processes in vascular territories acquires importance in the analysis
of the multi-scale circulatory cascade and the coupling between blood flow and cell function …
of the multi-scale circulatory cascade and the coupling between blood flow and cell function …