CircaKB: a comprehensive knowledgebase of circadian genes across multiple species

X Zhu, X Han, Z Li, X Zhou, SH Yoo… - Nucleic Acids …, 2024 - academic.oup.com
Circadian rhythms, which are the natural cycles that dictate various physiological processes
over a 24-h period, have been increasingly recognized as important in the management and …

Adaptation to photoperiod via dynamic neurotransmitter segregation

G Maddaloni, YJ Chang, RA Senft, SM Dymecki - Nature, 2024 - nature.com
Abstract Changes in the amount of daylight (photoperiod) alter physiology and behaviour,.
Adaptive responses to seasonal photoperiods are vital to all organisms—dysregulation …

[HTML][HTML] Circadian rhythm disruption and retinal dysfunction: a bidirectional link in Alzheimer's disease?

L Carrero, D Antequera, C Municio… - Neural Regeneration …, 2024 - journals.lww.com
Dysfunction in circadian rhythms is a common occurrence in patients with Alzheimer's
disease. A predominant function of the retina is circadian synchronization, carrying …

Sleep and Oxidative Stress: Current Perspectives on the Role of NRF2

S Davinelli, A Medoro, R Savino… - Cellular and Molecular …, 2024 - Springer
Sleep is a fundamental conserved physiological state across evolution, suggesting vital
biological functions that are yet to be fully clarified. However, our understanding of the …

[HTML][HTML] The role of circadian rhythm in neurological diseases: a translational perspective

W Huang, J Zong, Y Zhang, Y Zhou, L Zhang… - Aging and …, 2024 - ncbi.nlm.nih.gov
Intrinsic biological clocks drive the circadian rhythm, which coordinates the physiological
and pathophysiological processes in the body. Recently, a bidirectional relationship …

The association of night shift work with the risk of all-cause dementia and Alzheimer's disease: A longitudinal study of 245,570 UK biobank participants

Y Ling, S Yuan, X Huang, S Tan, T Huang, A Xu… - Journal of …, 2023 - Springer
Background The purpose of this research was to investigate a possible link between night
shift work and the development of all-cause dementia and Alzheimer's disease (AD), as well …

Circadian clock disruption promotes the degeneration of dopaminergic neurons in male Drosophila

M Majcin Dorcikova, LC Duret, E Pottié… - Nature …, 2023 - nature.com
Sleep and circadian rhythm disruptions are frequent comorbidities of Parkinson's disease
(PD), a disorder characterized by the progressive loss of dopaminergic (DA) neurons in the …

Targeting sleep and the circadian system as a novel treatment strategy for Parkinson's disease

B Feigl, SJG Lewis, O Rawashdeh - Journal of Neurology, 2024 - Springer
There is a growing appreciation of the wide range of sleep–wake disturbances that occur
frequently in Parkinson's disease. These are known to be associated with a range of motor …

Melatonin as a chronobiotic/cytoprotective agent in REM sleep behavior disorder

DP Cardinali, A Garay - Brain Sciences, 2023 - mdpi.com
Dream-enactment behavior that emerges during episodes of rapid eye movement (REM)
sleep without muscle atonia is a parasomnia known as REM sleep behavior disorder (RBD) …

Exploring the key parameters for indoor light intervention in treating neurodegenerative diseases: A systematic review

K Su, C Wang, J Xiang - Building and Environment, 2024 - Elsevier
Light, essential for health and well-being, has shown promise for treating neurodegenerative
diseases (NDDs). Indoor light intervention (ILI) has become a widely utilized approach in …