Background Circadian rhythm (CR) disturbance is intricately associated with Parkinson's
disease (PD). However, the involvement of CR-related mechanisms in the pathogenesis and …

Alzheimer's disease (AD) is a chronic neurodegenerative disorder characterized by
progressive loss of memory. Presently, AD is challenging to treat with current drug therapy …

Honeybees have been helpful insects since ancient centuries, and this benefit is not limited
to being a honey producer only. After the bee stings a person, pain, and swelling occur in …

Sleep and circadian rhythms are observed broadly throughout animal phyla and influence
neural plasticity and cognitive function. However, the few phylogenetically conserved …

Introduction The exact relationship between long-term shift work (SW) and cognitive
impairment (CI) has been poorly understood. The effects of the long-term rotating night SW …

Parkinson's disease (PD) is one of the most common neurodegenerative diseases.
Investigating individuals with the most identical genetic background is optimal for minimizing …

Parkinson's disease (PD) is characterized by a long prodromal period, during which patients
often have sleep disturbances. The histaminergic system and circadian rhythms play an …

Sleep is a fundamental conserved physiological state across evolution, suggesting vital
biological functions that are yet to be fully clarified. However, our understanding of the …

Accumulating evidence indicates that chronic circadian rhythm disruption is associated with
the development of neurodegenerative diseases induced by exposure to neurotoxic …

Circadian rhythm disorders pose major risks to human health and animal production activity,
and the hypothalamus is the center of circadian rhythm regulation. However, the epigenetic …