COSMOPharm: Drug–Polymer Compatibility of Pharmaceutical Amorphous Solid Dispersions from COSMO-SAC
The quantum mechanics-aided COSMO-SAC activity coefficient model is applied and
systematically examined for predicting the thermodynamic compatibility of drugs and …
systematically examined for predicting the thermodynamic compatibility of drugs and …
[HTML][HTML] Trends in amorphous solid dispersion drug products approved by the US Food and Drug Administration between 2012 and 2023
Abstract Forty-eight (48) drug products (DPs) containing amorphous solid dispersions
(ASDs) have been approved by the US Food and Drug Administration in the 12-year period …
(ASDs) have been approved by the US Food and Drug Administration in the 12-year period …
The step-wise dissolution method: An efficient DSC-based protocol for verification of predicted API–polymer compatibility
A Mathers, M Pechar, F Hassouna, M Fulem - International Journal of …, 2023 - Elsevier
The development of an amorphous solid dispersion (ASD) is a promising strategy for
improving the low bioavailability of many poorly water-soluble active pharmaceutical …
improving the low bioavailability of many poorly water-soluble active pharmaceutical …
[HTML][HTML] A unifying approach to drug-in-polymer solubility prediction: Streamlining experimental workflow and analysis
This method paper describes currently used experimental methods to predict the drug-in-
polymer solubility of amorphous solid dispersions and offers a combined approach for …
polymer solubility of amorphous solid dispersions and offers a combined approach for …
Predicting the Thermodynamic Properties of Complex Fluids and Their Mixtures
AK Nelson - 2023 - search.proquest.com
Developing reliable methods to predict the thermodynamic properties and phase behavior of
complex fluids is essential for accurate process modeling. Specifically, process modeling of …
complex fluids is essential for accurate process modeling. Specifically, process modeling of …