Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse physiological
functions. Its two isoforms (α and β) are widely expressed throughout the body in sensory …

Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide. Discovered 30
years ago, it is produced as a consequence of alternative RNA processing of the calcitonin …

Group 2 innate lymphoid cells (ILC 2s) play critical roles in the induction of type 2
inflammation, response to parasite infection, metabolic homeostasis, and tissue repair …

The calcitonin/CGRP family of peptides includes calcitonin, α and β CGRP, amylin,
adrenomedullin (AM) and adrenomedullin 2/intermedin (AM2/IMD). Their receptors consist …

The neuropeptides calcitonin gene-related peptide (CGRP) and pituitary adenylate cyclase-
activating polypeptide (PACAP) have emerged as mediators of migraine pathogenesis. Both …

It is known that interactions between nociceptors and dendritic cells (DCs) can modulate
immune responses in barrier tissues. However, our understanding of the underlying …

Migraine is a neurological disorder that manifests as a debilitating headache associated
with altered sensory perception. The neuropeptide calcitonin gene-related peptide (CGRP) …

Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

Migraine is a complex disorder characterized by recurrent episodes of headache, and is one
of the most prevalent and disabling neurological disorders. A key feature of migraine is that …

Background The clinical efficacy of migraine therapeutic agents directed towards the
calcitonin-gene related peptide (CGRP) pathway has confirmed the key role of this axis in …