Recent insights into the roles of circular RNAs in human brain development and neurologic diseases

S Najafi, SMA Zarch, J Majidpoor, S Pordel… - International Journal of …, 2023 - Elsevier
Circular RNAs (circRNAs) are a novel class of non-coding RNAs. They are single-stranded
RNA transcripts characterized with a closed loop structure making them resistant to …

microRNA-184 in the landscape of human malignancies: a review to roles and clinical significance

M Fattahi, D Rezaee, F Fakhari, S Najafi… - Cell Death …, 2023 - nature.com
MicroRNAs (miRNAs) are a class of non-coding RNAs (ncRNAs) with a short length of 19–
22 nucleotides. miRNAs are posttranscriptional regulators of gene expression involved in …

Long non-coding RNAs (lncRNAs); roles in tumorigenesis and potentials as biomarkers in cancer diagnosis

S Najafi, SH Khatami, M Khorsand, Z Jamali… - Experimental cell …, 2022 - Elsevier
New research has indicated that long non-coding RNAs (lncRNAs) play critical roles in a
broad range of biological processes, including the pathogenesis of many complex human …

Functional roles of lncRNA-TUG1 in hepatocellular carcinoma

M Farzaneh, M Ghasemian, F Ghaedrahmati… - Life Sciences, 2022 - Elsevier
Hepatocellular carcinoma (HCC) or hepatoma is malignant cancer that starts from the main
liver cells. Although various classical methods have been used for patients with HCC …

Liquid biopsy in colorectal cancer

S Najafi, J Majidpoor, K Mortezaee - Clinica Chimica Acta, 2023 - Elsevier
Liquid biopsy refers to a set of pathological samples retrieved from non-solid sources, such
as blood, cerebrospinal fluid, urine, and saliva through non-invasive or minimally invasive …

The MALAT1-breast cancer interplay: insights and implications

M Tufail - Expert Review of Molecular Diagnostics, 2023 - Taylor & Francis
Introduction Breast cancer (BC) is a major public health concern, and identifying new
biomarkers and therapeutic targets is critical to improving patient outcomes. MALAT1, a long …

Deep learning approaches for lncrna-mediated mechanisms: A comprehensive review of recent developments

Y Kim, M Lee - International journal of molecular sciences, 2023 - mdpi.com
This review paper provides an extensive analysis of the rapidly evolving convergence of
deep learning and long non-coding RNAs (lncRNAs). Considering the recent advancements …

LncRNA PKD2-2-3 对肺腺癌细胞增殖, 克隆形成, 迁移及侵袭能力的影响

贾利晴, 葛小路, 姜琳, 周晓燕 - 中国癌症杂志, 2023 - china-oncology.com
背景与目的: 长链非编码RNA (long non-coding RNA, lncRNA) 在肺腺癌患者中异常表达,
与肿瘤的发生, 发展和化疗耐药密切相关. 本研究旨在探讨lncRNA 蛋白激酶D2 (lncRNA PKD2 …

Tumor-educated platelets

S Najafi, Y Asemani, J Majidpoor, R Mahmoudi… - Clinica Chimica …, 2023 - Elsevier
Beyond traditional roles in homeostasis and coagulation, growing evidence suggests that
platelets also reflect malignant transformation in cancer. Platelets are present in the tumor …

A comprehensive overview of exosome lncRNAs: emerging biomarkers and potential therapeutics in endometriosis

M Wang, L Zheng, R Lin, S Ma, J Li… - Frontiers in …, 2023 - frontiersin.org
Endometriosis is a gynecological condition that significantly impacting women's daily lives.
In recent years, the incidence of endometriosis has been rising yearly and is now an …