Appreciation of the importance of Akkermansia muciniphila is growing, and it is becoming
increasingly relevant to identify preventive and/or therapeutic solutions targeting gut–liver …

Akkermansia muciniphila (A. muciniphila) is present in the human gut microbiota from
infancy and gradually increases in adulthood. The potential impact of the abundance of A …

Background and Purpose: Ciprofol (HSK3486), a novel 2, 6-disubstituted phenol derivative,
is a new intravenous anesthetic compound with a similar chemical structure to propofol …

Pyroptosis is a form of programmed cell death associated with activation of inflammasomes
and inflammatory caspases, proteolytic cleavage of gasdermin proteins (forming pores in the …

Background Doxorubicin (DOX) is a potent anticancer chemotherapeutic agent whose
clinical application is substantially constrained by its cardiotoxicity. The pathophysiology of …

The pathologies of many diseases are influenced by environmental temperature. As early as
the classical Roman age, people believed that exposure to cold weather was bad for …

Introduction Proprotein convertase subtilisin/kexin type 9 (PCSK9) is implicated in the
pathogenesis and progression of autoimmune disease. Patients with rheumatoid arthritis …

Metabolic diseases are comprehensive disease based on obesity. Numerous cumulative
studies have shown a certain correlation between the fluctuating abundance of Akkermansia …

Atrial fibrillation (AF) poses a serious healthcare burden on society due to its high morbidity
and the resulting serious complications such as thrombosis and heart failure. The principle …

Inflammation drives coronary artery disease and atherosclerosis implications. Lipoprotein
entry, retention, and oxidative modification cause endothelial damage, triggering innate and …