[HTML][HTML] Therapeutic potential of phenolic compounds in medicinal plants—Natural health products for human health

W Sun, MH Shahrajabian - Molecules, 2023 - mdpi.com
Phenolic compounds and flavonoids are potential substitutes for bioactive agents in
pharmaceutical and medicinal sections to promote human health and prevent and cure …

[HTML][HTML] Natural coumarin derivatives activating Nrf2 signaling pathway as lead compounds for the design and synthesis of intestinal anti-inflammatory drugs

LC Di Stasi - Pharmaceuticals, 2023 - mdpi.com
Nrf2 (nuclear factor erythroid 2-related factor 2) is a transcription factor related to stress
response and cellular homeostasis that plays a key role in maintaining the redox system …

Cold stimulation causes oxidative stress, inflammatory response and apoptosis in broiler heart via regulating Nrf2/HO-1 and NF-κB pathway

H Wei, T Li, Y Zhang, X Liu, R Gong, J Bao… - Journal of Thermal …, 2023 - Elsevier
To investigate the effect of cold stimulation on heart, 300 1-day-old female broilers were
divided into control (CON) and two cold stimulation (CS3 and CS9) groups. Birds in CON …

Eucalyptol relieves the toxicity of diisobutyl phthalate in Ctenopharyngodon idellus kidney cells through Keap1/Nrf2/HO-1 pathway: Apoptosis-autophagy crosstalk …

H Liu, W Sun, H Zhu, J Guo, M Liu, S Xu - Fish & shellfish immunology, 2022 - Elsevier
Diisobutyl phthalate (DiBP), one of the commonly used plasticizers in industry, is an
endocrine disruptor and environmental contaminant that can persist in water and threaten …

[HTML][HTML] Formononetin ameliorates renal dysfunction, oxidative stress, inflammation, and apoptosis and upregulates Nrf2/HO-1 signaling in a rat model of gentamicin …

OY Althunibat, MH Abukhalil, SH Aladaileh… - Frontiers in …, 2022 - frontiersin.org
Gentamicin (GEN) is a bactericidal aminoglycoside known to cause nephrotoxicity.
Formononetin (FN) is a potent flavonoid that exhibits numerous promising pharmacological …

[HTML][HTML] Cardioprotective effect of taxifolin against isoproterenol-induced cardiac injury through decreasing oxidative stress, inflammation, and cell death, and …

HM Obeidat, OY Althunibat, MA Alfwuaires… - Biomolecules, 2022 - mdpi.com
Oxidative stress and inflammation are key components in cardiovascular diseases and heart
dysfunction. Herein, we evaluated the protective effects of (+)-taxifolin (TAX), a potent …

[HTML][HTML] In an experimental myocardial infarction model, L-arginine pre-intervention may exert cardioprotective effects by regulating OTULIN levels and mitochondrial …

S Kaya, T Yalcın - Cell Stress and Chaperones, 2023 - Elsevier
The experimental myocardial infarction (MI) model originating from isoproterenol (ISO) is
frequently preferred in research due to its similarity to MI-induced damage in humans …

Comprehensive analysis of the immunological differences in the intestinal barrier of improved grass carp and their parents

H Tan, B Hu, W Liu, Y Wang, W He, Y Zhang, C Geng… - Aquaculture, 2023 - Elsevier
Disease-resistant grass carp (DR-GGC) was an improved grass carp developed by
backcrossing gynogenetic grass carp (GGC, female) with grass carp (Ctenopharyngodon …

[HTML][HTML] Intermittent mild cold stimulation alleviates cold stress-induced pulmonary fibrosis by inhibiting the TGF-β1/Smad signaling pathway in broilers

H Wei, Y Zhang, T Li, S Zhang, J Yin, Y Liu, L Xing… - Poultry Science, 2024 - Elsevier
To investigate the potential protective effect of intermittent cold stimulation on lung tissues of
broilers exposed to acute cold stress (ACS). A total of 384 one-day-old broilers were …

[HTML][HTML] Renoprotective and oxidative stress-modulating effects of taxifolin against cadmium-induced nephrotoxicity in mice

AI Algefare - Life, 2022 - mdpi.com
Cadmium (Cd) is an inessential trace metal that accumulates in the kidney and may lead to
renal toxicity by mediating oxidative stress (OS), inflammatory reactions, and apoptosis. The …