Natural products, and especially the active ingredients found in traditional Chinese medicine
(TCM), have a thousand-year-long history of clinical use and a strong theoretical basis in …

Medicinal plants have been used by mankind since ancient times, and many bioactive plant
secondary metabolites are applied nowadays both directly as drugs, and as raw materials …

Hot pepper (Capsicum annuum) fruits, usually termed as chili, have been used since ancient
times as food vegetables, flavoring ingredients, natural colorants, and in traditional …

In the last decade, the association between diet and cognitive function or dementia has
been largely investigated. In the present article, we systematically reviewed observational …

The transient receptor potential vanilloid-1 (TRPV1) is a non-specific cation channel known
for its sensitivity to pungent vanilloid compound (ie capsaicin) and noxious stimuli, including …

Over the last decade, increasing interest has been attracted towards the application of
artificial intelligence (AI) technology for analyzing and interpreting the biological or genetic …

Fungal endophytes are well-established sources of biologically active natural compounds
with many producing pharmacologically valuable specific plant-derived products. This …

This report explores the available curative molecules directed against hepatocellular
carcinoma (HCC). Limited efficiency as well as other drawbacks of existing molecules led to …

Neuropathic pain, caused by a lesion or disease affecting the somatosensory system, affects
between 3 and 17% of the general population. The treatment of neuropathic pain is …

Capsaicin is the primary bioactive substance in red chili peppers, which produces the
pungent flavor. During the past few decades, pharmacological benefits of capsaicin and its …