Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

The present review covers developments in studies of nanomaterials (NMs) in the
environment since our much cited review in 2008. We discuss novel insights into fate and …

The administration of nanoparticles (NPs) first faces the challenges of evading renal filtration
and clearance of reticuloendothelial system (RES). After that, NPs infiltrate through the …

Nanotechnology in medical applications, especially in oncology as drug delivery systems,
has recently shown promising results. However, although these advances have been …

The beneficial or deleterious effects of nanomedicines emerge from their complex
interactions with intracellular pathways and their subcellular fate. Moreover, the dynamic …

Surface charge on biomaterials is emerging as a crucial determinant of regulating cells
responses impacting cells signaling in tissue treatment. The dynamic cell-material …

PKH lipophilic dyes are highly fluorescent and stain membranes by intercalating their
aliphatic portion into the exposed lipid bilayer. They have established use in labeling and …

Many types of nanoparticles (NPs) are tested for use in medical products, particularly in
imaging and gene and drug delivery. For these applications, cellular uptake is usually a …

Polymeric materials have been used in a range of pharmaceutical and biotechnology
products for more than 40 years. These materials have evolved from their earlier use as …

Nanomedicines employ multiple endocytic pathways to enter cells. Their following fate is
interesting, but it is not sufficient understood currently. This review introduces the endocytic …