Targeting cancer cells with biotin–dendrimer conjugates

W Yang, Y Cheng, T Xu, X Wang, L Wen - European journal of medicinal …, 2009 - Elsevier
Star-burst dendrimers represent a superior carrier platform for targeted drug delivery.
Partially acetylated generation 5 (G5) polyamidoamine (PAMAM) dendrimer was conjugated …

Efficient gene delivery targeted to the brain using a transferrin‐conjugated polyethyleneglycol‐modified polyamidoamine dendrimer

RQ Huang, YH Qu, WL Ke, JH Zhu, YY Pei… - The FASEB …, 2007 - Wiley Online Library
The blood‐brain barrier (BBB) poses great difficulties for gene delivery to the brain. To
circumvent the BBB, we investigated a novel brain‐targeting gene vector based on the …

[HTML][HTML] Polymeric nanocarriers: A promising tool for early diagnosis and efficient treatment of colorectal cancer

M Haider, KZ Zaki, MR El Hamshary, Z Hussain… - Journal of advanced …, 2022 - Elsevier
Background Colorectal cancer (CRC) is the third most prevalent type of cancer for incidence
and second for mortality worldwide. Late diagnosis and inconvenient and expensive current …

Can controversial nanotechnology promise drug delivery?

VR Devadasu, V Bhardwaj, MNVR Kumar - Chemical reviews, 2013 - ACS Publications
Observing and visualizing objects, with the help of tools, which cannot be seen with the
naked eye, had always raised curiosity among the scientific community and given scientific …

Smart nanocarriers-based drug delivery for cancer therapy: An innovative and developing strategy

S Huda, MA Alam, PK Sharma - Journal of Drug Delivery Science and …, 2020 - Elsevier
Cancer is one of the leading causes of death but is surpassed by cardiovascular diseases.
Cancer is a disease categorized by the uncontrolled growth of cells worldwide with an …

Novel strategies to improve the anticancer action of 5-fluorouracil by using drug delivery systems

JL Arias - Molecules, 2008 - mdpi.com
Because of the fundamental importance of new therapeutic routes for cancer treatment, a
number of systems based on colloidal particles as vehicles for the delivery of the anticancer …

Glycodendrimeric nanoparticulate carriers of primaquine phosphate for liver targeting

D Bhadra, AK Yadav, S Bhadra, NK Jain - International journal of …, 2005 - Elsevier
In the present study it was intended to deliver primaquine phosphate (PP), a liver
schizonticide directly to liver cells using polypropyleneimine (PPI) dendrimers-coated …

Mannosylated solid lipid nanoparticles as vectors for site-specific delivery of an anti-cancer drug

A Jain, A Agarwal, S Majumder, N Lariya… - Journal of Controlled …, 2010 - Elsevier
The purpose of the present study was to investigate the tumor targeting potential of surface
tailored solid lipid nanoparticles (SLNs) loaded with an anti-cancer drug doxorubicin HCl …

Enabling individualized therapy through nanotechnology

JH Sakamoto, AL van de Ven, B Godin, E Blanco… - Pharmacological …, 2010 - Elsevier
Individualized medicine is the healthcare strategy that rebukes the idiomatic dogma of
'losing sight of the forest for the trees'. We are entering a new era of healthcare where it is no …

Loading of polymer nanocarriers: Factors, mechanisms and applications

A Kowalczuk, R Trzcinska, B Trzebicka… - Progress in polymer …, 2014 - Elsevier
The progress in synthetic polymer chemistry has allowed the precise design of hybrid and
multifunctional colloidal particles, which differ in type, size and shape, thus enhancing their …