The regulation and functions of DNA and RNA G-quadruplexes
DNA and RNA can adopt various secondary structures. Four-stranded G-quadruplex (G4)
structures form through self-recognition of guanines into stacked tetrads, and considerable …
structures form through self-recognition of guanines into stacked tetrads, and considerable …
DNA G-quadruplex structures: more than simple roadblocks to transcription?
J Robinson, F Raguseo, SP Nuccio… - Nucleic acids …, 2021 - academic.oup.com
It has been> 20 years since the formation of G-quadruplex (G4) secondary structures in
gene promoters was first linked to the regulation of gene expression. Since then, the …
gene promoters was first linked to the regulation of gene expression. Since then, the …
[HTML][HTML] The genomics of oxidative DNA damage, repair, and resulting mutagenesis
AR Poetsch - Computational and structural biotechnology journal, 2020 - Elsevier
Reactive oxygen species are a constant threat to DNA as they modify bases with the risk of
disrupting genome function, inducing genome instability and mutation. Such risks are due to …
disrupting genome function, inducing genome instability and mutation. Such risks are due to …
G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy
E Ruggiero, SN Richter - Nucleic acids research, 2018 - academic.oup.com
Abstract G-quadruplexes (G4s) are non-canonical nucleic acids secondary structures that
form within guanine-rich strands of regulatory genomic regions. G4s have been extensively …
form within guanine-rich strands of regulatory genomic regions. G4s have been extensively …
On the wrong DNA track: Molecular mechanisms of repeat-mediated genome instability
AN Khristich, SM Mirkin - Journal of Biological Chemistry, 2020 - ASBMB
Expansions of simple tandem repeats are responsible for almost 50 human diseases, the
majority of which are severe, degenerative, and not currently treatable or preventable. In this …
majority of which are severe, degenerative, and not currently treatable or preventable. In this …
RNA G-quadruplexes (rG4s): genomics and biological functions
Abstract G-quadruplexes (G4s) are non-classical DNA or RNA secondary structures that
have been first observed decades ago. Over the years, these four-stranded structural motifs …
have been first observed decades ago. Over the years, these four-stranded structural motifs …
G-Quadruplexes in RNA biology: recent advances and future directions
RNA G-quadruplexes (RG4s) are four-stranded structures known to control gene expression
mechanisms, from transcription to protein synthesis, and DNA-related processes. Their …
mechanisms, from transcription to protein synthesis, and DNA-related processes. Their …
G-quadruplex–R-loop interactions and the mechanism of anticancer G-quadruplex binders
Genomic DNA and cellular RNAs can form a variety of non-B secondary structures, including
G-quadruplex (G4) and R-loops. G4s are constituted by stacked guanine tetrads held …
G-quadruplex (G4) and R-loops. G4s are constituted by stacked guanine tetrads held …
Porphyrinoid biohybrid materials as an emerging toolbox for biomedical light management
V Almeida-Marrero, E van de Winckel… - Chemical Society …, 2018 - pubs.rsc.org
The development of photoactive and biocompatible nanomaterials is a current major
challenge of materials science and nanotechnology, as they will contribute to promoting …
challenge of materials science and nanotechnology, as they will contribute to promoting …