Fibrosis is universally observed in multiple aging-related diseases and progressions and is
characterized by excess accumulation of the extracellular matrix. Fibrosis occurs in various …

Many studies have revealed that circulating long noncoding RNAs (lncRNAs) regulate gene
and protein expression in the process of hepatic fibrosis. Liver fibrosis is a reversible wound …

Salvianolic acids, the most effective and abundant compounds extracted from Salvia
miltiorrhiza (Danshen), are well known for its good anti-oxidative activity. Danshen has been …

Carvedilol has been identified as a promising agent for the treatment of liver fibrosis.
Meanwhile, autophagy and apoptosis have been reported to play key roles in the activation …

Fibrosis is characterized by an abnormal accumulation of extracellular matrix (ECM)
constituents in the liver parenchyma that lead to hepatic cirrhosis. After liver injury, the …

The global prevalence of nonalcoholic fatty liver disease (NAFLD) or metabolic associated
fatty liver disease (MAFLD), as it is now known, has gradually increased. NAFLD is a …

Background The mechanism of bone marrow mesenchymal stem cells (BMSCs) in treating
hepatic fibrosis remains unclear. Methods TGF-β1-induced hepatic stellate cell (HSC)-T6 …

Long intergenic noncoding RNA p21 was mapped on the human chromosome 6p21. 2.
Accordingly, it was firstly described by promoting the p53-dependent apoptosis in the …

Liver fibrosis resulting from continuous long‐term hepatic damage represents a heavy
burden worldwide. Liver fibrosis is recognized as a complicated pathogenic mechanism with …

Hepatocellular carcinoma (HCC), commonly caused by liver fibrosis, is a global challenge
with high morbidity. Activation of hepatic stellate cells (HSCs) contributes to hepatic fibrosis …