Posterior reversible encephalopathy syndrome (PRES) is a neurotoxic state accompanied
by a unique brain imaging pattern typically associated with a number of complex clinical …

Bacterial sepsis and septic shock result from the overproduction of inflammatory mediators
as a consequence of the interaction of the immune system with bacteria and bacterial wall …

The outcome of encounters between Staphylococcus (S.) aureus and its human host ranges
from life-threatening infection through allergic reactions to symptom-free colonization. The …

BACKGROUND AND PURPOSE: The cause of “posterior reversible encephalopathy
syndrome”(PRES) is not established. We recently encountered several patients who …

Microbial Superantigens are a family of protein exotoxins that share the ability to trigger
excessive and aberrant activation of T cells. The best characterised are the staphylococcal …

Background. Staphylococcus aureus superantigens are associated with the pathogenesis of
toxic shock syndrome, but their involvement in septic shock is unknown. Methods. We …

Rapid overproduction of proinflammatory cytokines are characteristic of sepsis.
CD14dimCD16+ monocytes are thought to be major producers of cytokine and have been …

ABSTRACT PCR was employed to determine the presence of all known superantigen genes
(sea, seq, and tst) and of the exotoxin-like gene cluster (set) in 40 Staphylococcus aureus …

Pathophysiologic basis of sepsis: Considerations for future... : Critical Care Medicine
Pathophysiologic basis of sepsis: Considerations for future strategies of intervention : Critical …

In Staphylococcus aureus, 19 different superantigens (SAgs) have been described. Their
genes are all located on mobile genetic elements, such as pathogenicity islands, plasmids …