The oxylipin analog CS585 prevents platelet activation and thrombosis through activation of the prostacyclin receptor
L Stanger, A Yamaguchi, P Yalavarthi, S Lambert… - Blood, 2023 - ashpublications.org
Cardiovascular disease remains the primary cause of morbidity and mortality globally.
Platelet activation is critical for maintaining hemostasis and preventing the leakage of blood …
Platelet activation is critical for maintaining hemostasis and preventing the leakage of blood …
Genetic Determinants of Response to P2Y12 Inhibitors and Clinical Implications
LH Cavallari, JC Coons - Interventional cardiology clinics, 2024 - pubmed.ncbi.nlm.nih.gov
The CYP2C19 enzyme metabolizes clopidogrel, a prodrug, to its active form. Approximately
30% of individuals inherit a loss-of-function (LoF) polymorphism in the CYP2C19 gene …
30% of individuals inherit a loss-of-function (LoF) polymorphism in the CYP2C19 gene …