[HTML][HTML] Hepatitis B functional cure and immune response

JR Zheng, ZL Wang, B Feng - Frontiers in Immunology, 2022 - frontiersin.org
Hepatitis B virus (HBV) is a hepatotropic virus, which damage to hepatocytes is not direct,
but through the immune system. HBV specific CD4+ T cells can induce HBV specific B cells …

[HTML][HTML] Many Ways to Communicate—Crosstalk between the HBV-Infected Cell and Its Environment

AJ Walter, MA van de Klundert, S Jung - Pathogens, 2022 - mdpi.com
Chronic infection with the hepatitis B virus (HBV) affects an estimated 257 million people
worldwide and can lead to liver diseases such as cirrhosis and liver cancer. Viral replication …

[HTML][HTML] HBV immune tolerance of HBs-transgenic mice observed through parabiosis with WT mice

W Zhang, H Sun, R Sun, Z Lian, H Wei, Z Tian… - Frontiers in …, 2022 - frontiersin.org
It was extensively recognized that central tolerance to HBV exists in HBs-transgenic (Tg)
mice, however, the immune response to HBV vaccine may be inspired in adult HBs-Tg mice …

Fractional‐order models of hepatitis B virus infection with recycling effects of capsids

R Sutradhar, DC Dalal - Mathematical Methods in the Applied …, 2023 - Wiley Online Library
Hepatitis B virus (HBV) infection is a major public health concern throughout the world. It can
be treated effectively through proper medication and vaccination, although it is very difficult …

Infections after organ transplantation and immune response

A Elalouf - Transplant Immunology, 2023 - Elsevier
Organ transplantation has provided another chance of survival for end-stage organ failure
patients. Yet, transplant rejection is still a main challenging factor. Immunosuppressive drugs …

[HTML][HTML] The regulation of antiviral innate immunity through non-m6A RNA modifications

S Shen, LS Zhang - Frontiers in Immunology, 2023 - frontiersin.org
The post-transcriptional RNA modifications impact the dynamic regulation of gene
expression in diverse biological and physiological processes. Host RNA modifications play …

[HTML][HTML] Overview of the immunological mechanisms in hepatitis B virus reactivation: Implications for disease progression and management strategies

H Ma, QZ Yan, JR Ma, DF Li… - World Journal of …, 2024 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) reactivation is a clinically significant challenge in disease
management. This review explores the immunological mechanisms underlying HBV …

The dual role of regulatory T cells in hepatitis B virus infection and related hepatocellular carcinoma

J He, R Miao, Y Chen, H Wang, M Liu - Immunology, 2024 - Wiley Online Library
Hepatocellular carcinoma (HCC) is a major contributor to cancer‐related deaths worldwide.
Hepatitis B virus (HBV) infection is a major etiologic factor leading to HCC. While there have …

[HTML][HTML] Sulforaphane effectively inhibits HBV by altering Treg/Th17 immune balance and the MIF-macrophages polarizing axis in vitro and in vivo

R Xu, Y Wu, X Xiang, X Lv, M He, C Xu, G Lai, T Xiang - Virus Research, 2024 - Elsevier
Abstract Background Hepatitis B virus (HBV) infection is a major public health problem. After
HBV infection, viral antigens shift the immune balance in favor of viral escape. Sulforaphane …

CCR2+ TREM-1+ monocytes promote natural killer T cell dysfunction contributing towards HBV disease progression

X Wu, W Zhao, Q Miao, S Shi, B Wei, L Luo… - Immunologic Research, 2024 - Springer
Natural killer T (NKT) cells are amongst the most important innate immune cells against
hepatitis B virus (HBV) infection. Moreover, previous studies have shown that HBV infection …