Therapeutic potential of GLP-2 analogs in gastrointestinal disorders: current knowledge, nutritional aspects, and future perspectives

D Kounatidis, NG Vallianou, D Tsilingiris… - Current Nutrition …, 2022 - Springer
Abstract Purpose of Review Although Glucagon-like peptide (GLP)-1 receptor agonists have
been used for almost two decades in the treatment of diabetes mellitus type 2 and, lately, in …

Impact of total parenteral nutrition on gut microbiota in pediatric population suffering intestinal disorders

T Cerdó, JA García-Santos, A Rodríguez-Pöhnlein… - Nutrients, 2022 - mdpi.com
Parenteral nutrition (PN) is a life-saving therapy providing nutritional support in patients with
digestive tract complications, particularly in preterm neonates due to their gut immaturity …

Long-term treatment with teduglutide: a 48-week open-label single-center clinical trial in children with short bowel syndrome

C Lambe, C Talbotec, N Kapel… - The American Journal of …, 2023 - Elsevier
Background Short bowel syndrome (SBS) is the main cause of intestinal failure in children.
Objectives This single-center study evaluated the safety and efficacy of teduglutide in …

Nutrition and intestinal rehabilitation of children with short bowel syndrome: a position paper of the ESPGHAN committee on nutrition. Part 2: long-term follow-up on …

L Norsa, O Goulet, D Alberti, B DeKooning… - Journal of pediatric …, 2023 - journals.lww.com
Short bowel syndrome (SBS) is the leading cause of intestinal failure (IF) in children. The
preferred treatment for IF is parenteral nutrition which may be required until adulthood. The …

Pediatric Home Parenteral Nutrition in France: A six years national survey

O Goulet, A Breton, ME Coste, B Dubern… - Clinical Nutrition, 2021 - Elsevier
Summary Background and aims Home Parenteral Nutrition (HPN) is the cornerstone
management for children suffering from chronic intestinal failure (CIF). In France, HPN is …

Lipid emulsion use in pediatric patients requiring long‐term parenteral nutrition

OJ Goulet, W Cai, JM Seo - Journal of Parenteral and Enteral …, 2020 - Wiley Online Library
The ability to deliver nutrients via parenteral nutrition (PN) has markedly improved the
prognosis of infants and children with intestinal failure. Technical refinements and advances …

Optimizing nutritional strategies to prevent necrotizing enterocolitis and growth failure after bowel resection

L Moschino, M Duci, F Fascetti Leon, L Bonadies… - Nutrients, 2021 - mdpi.com
Necrotizing enterocolitis (NEC), the first cause of short bowel syndrome (SBS) in the
neonate, is a serious neonatal gastrointestinal disease with an incidence of up to 11% in …

[HTML][HTML] Prediction, identification and progression of histopathological liver disease activity in children with intestinal failure

A Mutanen, J Lohi, L Merras-Salmio, A Koivusalo… - Journal of …, 2021 - Elsevier
Background & Aims Diagnostic criteria, progression risk and optimal monitoring for intestinal
failure (IF)-associated liver disease (IFALD) remain undefined. We assessed predictors, non …

[HTML][HTML] Featuring molecular regulation of bile acid homeostasis in pediatric short bowel syndrome

A Mutanen, MP Pakarinen - Clinics and Research in Hepatology and …, 2023 - Elsevier
Background Disturbed bile acid homeostasis may foster development of short bowel
syndrome (SBS) associated liver disease during and after weaning off parenteral nutrition …

Safety findings in pediatric patients during long‐term treatment with teduglutide for short‐bowel syndrome–associated intestinal failure: pooled analysis of 4 clinical …

S Hill, BA Carter, V Cohran, S Horslen… - Journal of Parenteral …, 2021 - Wiley Online Library
Background This analysis assessed combined safety data from 4 clinical studies of
teduglutide in pediatric patients with short‐bowel syndrome–associated intestinal failure …