Molecular inputs to chromatin via cellular metabolism are modifiers of the epigenome. These
inputs—which include both nutrient availability as a result of diet and growth factor signalling …

Alcohol use disorders consist of disorders characterised by compulsive heavy alcohol use
and loss of control over alcohol intake. Alcohol use disorders are some of the most prevalent …

Importance Alcohol use disorder affects more than 28.3 million people in the United States
and is associated with increased rates of morbidity and mortality. Objective To compare …

Treatment of Opioid-Use Disorders | NEJM Skip to main content NEJM Group Follow Us
Facebook Twitter Instagram YouTube LinkedIn Prepare to become a physician, build your …

Importance Alcohol use disorders cause substantial morbidity and early mortality yet remain
greatly undertreated. Medications are considerably underused. Objective To conduct a …

People with alcohol-related liver disease (ALD) experience stigma and discrimination. This
review summarises the evidence on stigma in healthcare and its implications for people with …

Assessments of lysergic acid diethylamide (LSD) in the treatment of alcoholism have not
been based on quantitative meta-analysis. Hence, we performed a meta-analysis of …

Recognition and Management of Withdrawal Delirium (Delirium Tremens) | NEJM Skip to main
content NEJM Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare to …

Medicine is an ever-changing science. As new research and clinical experience broaden
our knowledge, changes in treatment and drug therapy are required. The authors and the …

Alcohol abuse disorder is a serious condition, implicating more than 15 million people aged
12 years and older in 2019 in the United States. Ethanol (or ethyl alcohol) is mainly oxidized …