Background: Despite an increasing body of research highlighting their efficacy to treat a
broad range of medical conditions, psychedelic drugs remain a controversial issue among …

Psychiatric disorders are highly prevalent, often devastating diseases that negatively impact
the lives of millions of people worldwide. Although their etiological and diagnostic …

Psilocybin therapy shows antidepressant potential, but its therapeutic actions are not well
understood. We assessed the subacute impact of psilocybin on brain function in two clinical …

Psychedelics are a unique class of drug that commonly produce vivid hallucinations as well
as profound psychological and mystical experiences. A grouping of interconnected brain …

Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

The use of low sub-perceptual doses of psychedelics (“microdosing”) has gained popularity
in recent years. Although anecdotal reports claim multiple benefits associated with this …

Recent controversies have arisen regarding claims of uncritical positive regard and hype
surrounding psychedelic drugs and their therapeutic potential. Criticisms have included that …

The resurgence of Western psychedelic research and practice has led to increasing
concerns from many Indigenous Nations regarding cultural appropriation, lack of recognition …

4-Phosphoryloxy-N, N-dimethyltryptamine (psilocybin) is a naturally occurring tertiary amine
found in many mushroom species. Psilocybin is a prodrug for 4-hydroxy-N, N …

Modern psychedelic research remains in an early phase, and the eventual introduction of
psychedelics into clinical practice remains in doubt. In this piece, we discuss the role of …