Helicobacter pylori (H. pylori) is one of the most common human pathogens, affecting half of
the world's population. Approximately 20% of the infected patients develop gastric ulcers or …

The Hippo signaling pathway is a highly conserved pathway involved in tissue development
and regeneration that controls organ size through the regulation of cell proliferation and …

Background Tumor recurrence, the chief reason for poor prognosis of glioma, is largely
attributed to glioma stem cells (GSCs) and epithelial-mesenchymal transition (EMT) …

Background Due to the hypoxia and nutrient deficiency microenvironment, glioblastoma
(GBM) exhibits high autophagy activity and autophagy plays an important role in the …

Yes-associated protein (YAP) is a significant downstream protein in the Hippo signaling
pathway with important functions in cell proliferation, apoptosis, invasion and migration. YAP …

Ependymoma with YAP1‐MAMLD1 fusion is a rare, recently described supratentorial
neoplasm of childhood, with few cases published so far. We report on 15 pediatric patients …

Lung cancer is the leading cause of cancer death in the world and there is no current
treatment able to efficiently treat the disease as the tumor is often diagnosed at an advanced …

The Hippo and Wnt signalling pathways play crucial roles in maintaining tissue homeostasis
and organ size by orchestrating cell proliferation, differentiation and apoptosis. These …

Although radiotherapy is a well-known effective non-surgical treatment for malignant
gliomas, the therapeutic efficacy is severely limited due to the radioresistance of tumor cells …

Background After diagnosis, glioblastoma (GBM) patients undertake tremendous
psychological problems such as anxiety and depression, which may contribute to GBM …