Role of vitamin D in targeting cancer and cancer stem cell populations and its therapeutic implications

JB Marigoudar, D Sarkar, YM Yuguda, RF Abutayeh… - Medical Oncology, 2022 - Springer
Cancer is recognized globally as the second-most dominating and leading cause of
morbidities. Fighting the global health epidemic threat posed by cancer requires progress …

Ethnicity as modifier of risk for Vitamin D receptors polymorphisms: Comprehensive meta-analysis of all cancer sites

P Gnagnarella, S Raimondi, V Aristarco… - Critical reviews in …, 2021 - Elsevier
Vitamin D receptors polymorphisms are found to be associated with several cancers. Since
their prevalence vary across ethnicities and ethnicity itself seems to influence the cancer …

[HTML][HTML] 1, 25-Dihydroxyvitamin D deficiency induces sarcopenia by inducing skeletal muscle cell senescence

S Yu, B Ren, H Chen, D Goltzman, J Yan… - American journal of …, 2021 - ncbi.nlm.nih.gov
Abstract To determine if 1, 25 (OH) 2 D deficiency can induce age-related sarcopenia, the
skeletal muscular phenotype of male wild-type (WT) and Cyp27b1 knockout (KO) mice were …

Pyrroloquinoline quinone alleviates natural aging‐related osteoporosis via a novel MCM3‐Keap1‐Nrf2 axis‐mediated stress response and Fbn1 upregulation

J Li, J Zhang, Q Xue, B Liu, R Qin, Y Li, Y Qiu… - Aging …, 2023 - Wiley Online Library
Age‐related osteoporosis is associated with increased oxidative stress and cellular
senescence. Pyrroloquinoline quinone (PQQ) is a water‐soluble vitamin‐like compound that …

Association of vitamin D status with redox balance and insulin resistance and its predicting ability for subclinical pregnancy toxemia in pregnant sheep

M Nisar, SA Beigh, AQ Mir, SA Hussain, AA Dar… - Domestic Animal …, 2024 - Elsevier
The study aimed to evaluate the role of vitamin D on redox balance, insulin resistance and
its predicting value for subclinical pregnancy toxemia (SPT) in pregnant ewes. At four weeks …

Low-dose vitamin D protects hyperoxia-induced bronchopulmonary dysplasia by inhibiting neutrophil extracellular traps

C Chen, H Weng, X Zhang, S Wang, C Lu, H Jin… - Frontiers in …, 2020 - frontiersin.org
Background and Objective: As bronchopulmonary dysplasia (BPD) can lead to considerable
mortality and morbidity, this disease is the focus of attention in neonatology. Vitamin D (VD) …

Vitamin D Deficiency Aggravates Hepatic Oxidative Stress and Inflammation during Chronic Alcohol‐Induced Liver Injury in Mice

CQ Hu, QL Bo, LL Chu, YD Hu, L Fu… - Oxidative Medicine …, 2020 - Wiley Online Library
Vitamin D deficiency has been reported in alcoholics. This study is aimed at evaluating the
effects of vitamin D deficiency on chronic alcohol‐induced liver injury in mice. Mice were fed …

Micronutrients and Breast Cancer Progression: A Systematic Review

O Cuenca-Micó, C Aceves - Nutrients, 2020 - mdpi.com
Epidemiological studies on micronutrient consumption have reported protective associations
in the incidence and/or progression of various cancer types. Supplementation with some of …

Vitamin D metabolite profile in cholecalciferol-or calcitriol-supplemented healthy and mammary gland tumor-bearing mice

A Anisiewicz, K Kowalski, J Banach, N Łabędź… - Nutrients, 2020 - mdpi.com
To analyze if the prometastatic activity of calcitriol (active vitamin D3 metabolite), which was
previously observed in a 4T1 breast cancer model, is also found in other breast cancers, and …

P16INK4a Deletion Ameliorates Damage of Intestinal Epithelial Barrier and Microbial Dysbiosis in a Stress-Induced Premature Senescence Model of Bmi-1 …

J Zhou, C Hou, H Chen, Z Qin, Z Miao… - Frontiers in Cell and …, 2021 - frontiersin.org
This study aimed to determine whether Bmi-1 deficiency leads to intestinal epithelial barrier
destruction and microbiota dysfunction, which members of the microbial community alter …